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• W60153527 startingPage "nrs.04003" @default.
• W60153527 abstract "The nuclear receptor corepressors NCoR and SMRT repress gene transcription by recruiting a histone deacetylase complex. Their roles in PPARgamma action have been controversial. Recent evidence, however, suggests that NCoR and SMRT repress PPARgamma-mediated transcriptional activity on specific promoters in the adipocyte. In addition, by repressing PPARgamma action, these corepressors inhibit the ability of adipocyte differentiation to proceed. A further understanding of corepressor action in the adipocyte will provide insight into the balance of forces regulating adipogenesis, insulin sensitivity, and Type 2 diabetes mellitus." @default.
• W60153527 created "2016-06-24" @default.
• W60153527 creator A5046558877 @default.
• W60153527 date "2006-01-01" @default.
• W60153527 modified "2023-09-28" @default.
• W60153527 title "Nuclear Receptor Corepressors and PPARγ" @default.
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• W60153527 doi "https://doi.org/10.1621/nrs.04003" @default.
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