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- W60160136 abstract "Department of Anatomy, College of Medicine, Chungnam National University, Taejon, South Korea(Received 27 September 2010; Accepted 10 December 2010)Protein disulfide isomerase (PDI) catalyzes the oxida-tion of disulfides and the isomerizatiob of incorrectdisulfides in new polypeptides during folding in theoxidizing environment of the endoplasmic reticulum(ER). To increase recombinant protein hSCF (humanstem cell factor) production, we have developedexpression system using the Bombyx mori PDI (bPDI)as a fusion partner. bPDI gene fusion was found toimprove the production of recombinant hSCFs. Thus,we conclude that bPDI gene fusion will be very usefulfor the large-scale production of biologically activerecombinant proteins.Key words:Bombyx mori, Protein Disulfide Isomerase(PDI), Stem Cell Factor (SCF)" @default.
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- W60160136 date "2010-01-01" @default.
- W60160136 modified "2023-09-23" @default.
- W60160136 title "Expression of Recombinant Human Stem Cell Factor (hSCF) Protein using Bombyx mori Protein Disulfide Isomerase (bPDI)" @default.
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