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- W602543793 abstract "Salivary fluid is an exocrine secretion consisting of approximately 99% water, and contains a variety of electrolytes and proteins, including enzymes, immunoglobulins and other antimicrobial factors. These components interact and are responsible for the various functions attributed to saliva. Secretory immunoglobulin A (SIgA) is the largest immunological component of saliva with the ability to neutralize viruses, bacteria and toxins. It serves as an effective biological barrier by being able to aggregate bacteria, inhibiting their adherence to oral tissues . The regulation of immune function is linked to the increased incidence of malignancy, infectious disease, and autoimmune diseases. Respiratory infections, such as pneumonia and influenza, including upper respiratory tract infections, are particularly common and can cause serious illnesses among the disabled, children , and the elderly. In preliminary studies, the production of SIgA in the mouth has been reported; however, production of SIgA in the airway and lungs is unknown. The collection of exhaled breath condensate (EBC) is a recently developed technique for obtaining samples from the airways and lungs, which contains biomarkers including such as adenosine, hydrogen peroxide, isoprostanes, leukotrienes and cytokines. Journal of Analytical Bio-Science Vol. 33, No 3 (2010)" @default.
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- W602543793 date "2010-01-01" @default.
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- W602543793 title "Analysis of secretory immunoglobulin A concentration in saliva and exhaled breath condensate" @default.
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