FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W60475301> ?p ?o ?g. }

• W60475301 abstract "Gastrointestinal stromal tumors (GIST) are the most frequent sarcomas but were underdiagnosed until the beginning of this century. GIST derive from interstitial cells of Cajal and may develop all along the digestive tract. GIST are characterized by the expression of KIT (CD117), and also DOG-1, which was recently discovered by transcriptome analysis. Gain-of-function mutations of the tyrosine kinase receptors KIT and PDGFRA are present in 85% of cases. More than 150 different mutations have been reported, mostly located in exon 11 of the KIT gene. Detection of these mutations may be useful to confirm the diagnosis and to evaluate the prognosis. Mutations also have predictive value. For example, patients with metastatic GIST and a duplication of KIT exon 9 should receive twice the usual dose of imatinib, while GIST with the PDGFRA p. D842 V mutation are resistant to imatinib. This article presents the main pathologic characteristics of GIST and the important insights that GIST research has provided for oncology in general." @default.
• W60475301 created "2016-06-24" @default.
• W60475301 creator A5070179654 @default.
• W60475301 date "2012-04-01" @default.
• W60475301 modified "2023-10-18" @default.
• W60475301 title "Histologie et biologie moléculaire des GIST" @default.
• W60475301 cites W1549034776 @default.
• W60475301 cites W1965027830 @default.
• W60475301 cites W2006556639 @default.
• W60475301 cites W2010415450 @default.
• W60475301 cites W2024324841 @default.
• W60475301 cites W2040381070 @default.
• W60475301 cites W2042285483 @default.
• W60475301 cites W2043205182 @default.
• W60475301 cites W2059242879 @default.
• W60475301 cites W2065406815 @default.
• W60475301 cites W2068926954 @default.
• W60475301 cites W2096223992 @default.
• W60475301 cites W2101214437 @default.
• W60475301 cites W2102368865 @default.
• W60475301 cites W2103322585 @default.
• W60475301 cites W2108431450 @default.
• W60475301 cites W2109361235 @default.
• W60475301 cites W2111662961 @default.
• W60475301 cites W2118049258 @default.
• W60475301 cites W2122377651 @default.
• W60475301 cites W2122573984 @default.
• W60475301 cites W2123571541 @default.
• W60475301 cites W2126372498 @default.
• W60475301 cites W2128662774 @default.
• W60475301 cites W2150501295 @default.
• W60475301 cites W2152430532 @default.
• W60475301 cites W2152769688 @default.
• W60475301 cites W2161080750 @default.
• W60475301 cites W2167634320 @default.
• W60475301 cites W2171620774 @default.
• W60475301 cites W2276801579 @default.
• W60475301 cites W2324850882 @default.
• W60475301 cites W2525579613 @default.
• W60475301 doi "https://doi.org/10.1016/s0001-4079(19)31772-8" @default.
• W60475301 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23550446" @default.
• W60475301 hasPublicationYear "2012" @default.
• W60475301 type Work @default.
• W60475301 sameAs 60475301 @default.
• W60475301 citedByCount "7" @default.
• W60475301 countsByYear W604753012014 @default.
• W60475301 countsByYear W604753012015 @default.
• W60475301 countsByYear W604753012017 @default.
• W60475301 countsByYear W604753012018 @default.
• W60475301 countsByYear W604753012019 @default.
• W60475301 countsByYear W604753012020 @default.
• W60475301 crossrefType "journal-article" @default.
• W60475301 hasAuthorship W60475301A5070179654 @default.
• W60475301 hasConcept C10205521 @default.
• W60475301 hasConcept C104317684 @default.
• W60475301 hasConcept C142724271 @default.
• W60475301 hasConcept C16930146 @default.
• W60475301 hasConcept C201539569 @default.
• W60475301 hasConcept C204232928 @default.
• W60475301 hasConcept C2775922572 @default.
• W60475301 hasConcept C2776839831 @default.
• W60475301 hasConcept C2777007597 @default.
• W60475301 hasConcept C2777583451 @default.
• W60475301 hasConcept C2778729363 @default.
• W60475301 hasConcept C28328180 @default.
• W60475301 hasConcept C3019892230 @default.
• W60475301 hasConcept C36823959 @default.
• W60475301 hasConcept C37307934 @default.
• W60475301 hasConcept C502942594 @default.
• W60475301 hasConcept C54355233 @default.
• W60475301 hasConcept C71924100 @default.
• W60475301 hasConcept C86803240 @default.
• W60475301 hasConceptScore W60475301C10205521 @default.
• W60475301 hasConceptScore W60475301C104317684 @default.
• W60475301 hasConceptScore W60475301C142724271 @default.
• W60475301 hasConceptScore W60475301C16930146 @default.
• W60475301 hasConceptScore W60475301C201539569 @default.
• W60475301 hasConceptScore W60475301C204232928 @default.
• W60475301 hasConceptScore W60475301C2775922572 @default.
• W60475301 hasConceptScore W60475301C2776839831 @default.
• W60475301 hasConceptScore W60475301C2777007597 @default.
• W60475301 hasConceptScore W60475301C2777583451 @default.
• W60475301 hasConceptScore W60475301C2778729363 @default.
• W60475301 hasConceptScore W60475301C28328180 @default.
• W60475301 hasConceptScore W60475301C3019892230 @default.
• W60475301 hasConceptScore W60475301C36823959 @default.
• W60475301 hasConceptScore W60475301C37307934 @default.
• W60475301 hasConceptScore W60475301C502942594 @default.
• W60475301 hasConceptScore W60475301C54355233 @default.
• W60475301 hasConceptScore W60475301C71924100 @default.
• W60475301 hasConceptScore W60475301C86803240 @default.
• W60475301 hasLocation W604753011 @default.
• W60475301 hasLocation W604753012 @default.
• W60475301 hasOpenAccess W60475301 @default.
• W60475301 hasPrimaryLocation W604753011 @default.
• W60475301 hasRelatedWork W1500208871 @default.
• W60475301 hasRelatedWork W1521633337 @default.
• W60475301 hasRelatedWork W1802922849 @default.
• W60475301 hasRelatedWork W1980758734 @default.
• W60475301 hasRelatedWork W1990406748 @default.

• next