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- W60561295 abstract "Highly purified guinea pig C3a was obtained after specific cleavage of isolated C3 by the alternative pathway enzyme VF-B in a one step procedure. It turned out to be a low molecular weight peptide with basic character (M.W. 9500; isoelectric point above 9.4). C3a represents an antigenetic determinant of its own in the native C3 molecule, different from the B determinant. Guinea pig C3a is resistant to 100°C for 10 minutes. Its smooth muscle contracting activity can be destroyed by trypsin and carboxypeptidase B. These findings indicate that guinea pig C3a is quite similar to human C3a." @default.
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- W60561295 date "1978-03-01" @default.
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- W60561295 title "The Anaphylatoxic Peptide C3a of Guinea Pig Complement" @default.
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- W60561295 doi "https://doi.org/10.1016/s0340-904x(78)80028-1" @default.
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