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• W60574671 startingPage "131" @default.
• W60574671 abstract "The co-prevalence of helminth and HIV-1 infections in sub-Saharan Africa has fueled the suspicion that helminth infections constitute an important factor contributing to the high HIV prevalence in this region. Furthermore, it has been hypothesized that anti-helminthic treatment of co-infected HIV-positive patients is a potentially cost effective public health measurement that delays HIV disease progression and thus eligibility to antiretroviral therapy. Here we review the scientific data on the interaction between different helminth species and HIV on an epidemiological level and address pathogenic mechanisms that have been hypothesized to increase HIV susceptibility or rate of disease progression in helminth-HIV co-infected patients. We first focus on the basic concepts of HIV transmission, pathogenesis and then aim to consolidate the available data from human cohort studies, animal models and in vitro experiments to provide a coherent overview on the current state of knowledge in this field." @default.
• W60574671 created "2016-06-24" @default.
• W60574671 creator A5000953405 @default.
• W60574671 creator A5029733628 @default.
• W60574671 date "2014-01-01" @default.
• W60574671 modified "2023-09-24" @default.
• W60574671 title "Immune System Modulation by Helminth Infections: Potential Impact on HIV Transmission and Disease Progression" @default.
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