Matches in SemOpenAlex for { <https://semopenalex.org/work/W60740702> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W60740702 endingPage "73" @default.
- W60740702 startingPage "269" @default.
- W60740702 abstract "The reversible phosphorylation of structural and regulatory proteins in eucaryotic cells is one of the most important regulatory mechanisms. Protein tyrosine phosphatases (PTP) regulate a wide range of signal transduction pathways that control many cellular processes such as cell proliferation, differentiation and growth. Disorder in PTP gene expression is implicated in the development of cancer, autoimmune and neurodegenerative diseases. The active sites of these enzymes are characterized by the consensus sequence containing cysteine which is essential for enzyme activity and highly susceptible to oxidation. Reversible oxidation of the catalytic cysteine is becoming recognized as a general mechanism for regulation of PTP enzymatic activity. These findings suggest that protein tyrosine phosphatases may be considered as very sensitive markers of oxidative stress. Many studies have demonstrated that the production of reactive oxygen species during oxidative stress can inactivate protein tyrosine phosphatases." @default.
- W60740702 created "2016-06-24" @default.
- W60740702 creator A5001083223 @default.
- W60740702 creator A5027342673 @default.
- W60740702 creator A5031892194 @default.
- W60740702 creator A5034283298 @default.
- W60740702 creator A5040501531 @default.
- W60740702 creator A5057335112 @default.
- W60740702 date "2010-01-01" @default.
- W60740702 modified "2023-09-28" @default.
- W60740702 title "[Protein tyrosine phosphatases--endogenous markers of oxidative stress]." @default.
- W60740702 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21117314" @default.
- W60740702 hasPublicationYear "2010" @default.
- W60740702 type Work @default.
- W60740702 sameAs 60740702 @default.
- W60740702 citedByCount "3" @default.
- W60740702 countsByYear W607407022013 @default.
- W60740702 countsByYear W607407022015 @default.
- W60740702 crossrefType "journal-article" @default.
- W60740702 hasAuthorship W60740702A5001083223 @default.
- W60740702 hasAuthorship W60740702A5027342673 @default.
- W60740702 hasAuthorship W60740702A5031892194 @default.
- W60740702 hasAuthorship W60740702A5034283298 @default.
- W60740702 hasAuthorship W60740702A5040501531 @default.
- W60740702 hasAuthorship W60740702A5057335112 @default.
- W60740702 hasConcept C11960822 @default.
- W60740702 hasConcept C178666793 @default.
- W60740702 hasConcept C181199279 @default.
- W60740702 hasConcept C185592680 @default.
- W60740702 hasConcept C2776151105 @default.
- W60740702 hasConcept C2776165026 @default.
- W60740702 hasConcept C2777553839 @default.
- W60740702 hasConcept C2779201268 @default.
- W60740702 hasConcept C48349386 @default.
- W60740702 hasConcept C55493867 @default.
- W60740702 hasConcept C57600042 @default.
- W60740702 hasConcept C62478195 @default.
- W60740702 hasConcept C85528070 @default.
- W60740702 hasConcept C86803240 @default.
- W60740702 hasConcept C87325107 @default.
- W60740702 hasConcept C95444343 @default.
- W60740702 hasConcept C97029542 @default.
- W60740702 hasConceptScore W60740702C11960822 @default.
- W60740702 hasConceptScore W60740702C178666793 @default.
- W60740702 hasConceptScore W60740702C181199279 @default.
- W60740702 hasConceptScore W60740702C185592680 @default.
- W60740702 hasConceptScore W60740702C2776151105 @default.
- W60740702 hasConceptScore W60740702C2776165026 @default.
- W60740702 hasConceptScore W60740702C2777553839 @default.
- W60740702 hasConceptScore W60740702C2779201268 @default.
- W60740702 hasConceptScore W60740702C48349386 @default.
- W60740702 hasConceptScore W60740702C55493867 @default.
- W60740702 hasConceptScore W60740702C57600042 @default.
- W60740702 hasConceptScore W60740702C62478195 @default.
- W60740702 hasConceptScore W60740702C85528070 @default.
- W60740702 hasConceptScore W60740702C86803240 @default.
- W60740702 hasConceptScore W60740702C87325107 @default.
- W60740702 hasConceptScore W60740702C95444343 @default.
- W60740702 hasConceptScore W60740702C97029542 @default.
- W60740702 hasIssue "3" @default.
- W60740702 hasLocation W607407021 @default.
- W60740702 hasOpenAccess W60740702 @default.
- W60740702 hasPrimaryLocation W607407021 @default.
- W60740702 hasRelatedWork W1481623449 @default.
- W60740702 hasRelatedWork W1530589760 @default.
- W60740702 hasRelatedWork W1727895137 @default.
- W60740702 hasRelatedWork W179041473 @default.
- W60740702 hasRelatedWork W1967124450 @default.
- W60740702 hasRelatedWork W1972490217 @default.
- W60740702 hasRelatedWork W2017085995 @default.
- W60740702 hasRelatedWork W2047780246 @default.
- W60740702 hasRelatedWork W2053519292 @default.
- W60740702 hasRelatedWork W2055665256 @default.
- W60740702 hasRelatedWork W2072933237 @default.
- W60740702 hasRelatedWork W2081500362 @default.
- W60740702 hasRelatedWork W2093238964 @default.
- W60740702 hasRelatedWork W2115827933 @default.
- W60740702 hasRelatedWork W2367431408 @default.
- W60740702 hasRelatedWork W2890097187 @default.
- W60740702 hasRelatedWork W2898642823 @default.
- W60740702 hasRelatedWork W2898913070 @default.
- W60740702 hasRelatedWork W2986119369 @default.
- W60740702 hasRelatedWork W3180848588 @default.
- W60740702 hasVolume "56" @default.
- W60740702 isParatext "false" @default.
- W60740702 isRetracted "false" @default.
- W60740702 magId "60740702" @default.
- W60740702 workType "article" @default.