Matches in SemOpenAlex for { <https://semopenalex.org/work/W60751609> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W60751609 abstract "Purpose:To study the relationship between Fas/FasL expression and apoptosis of colon adenocarcinoma cell lines induced by chemotherapeutic drugs and to screen out hypersensitive drugs. Methods:Colon adenocarcinoma cell lines LS174T and LoVo were incubated respectively in cultural media with DDP,MMC,5 FU and EPI at concentrations of PPC(plasma peak concentration),1/10 PPC,1/5 PPC,5 PPC and 10 PPC. Fas/FasL expression and apoptosis were assessed by FACScan, and DNA ladder was examined by agarose gel electrophoresis. Results:In LS174T cells, Fas expression and apoptosis of DDP group, MMC group and EPI group reached their highest peaks at 1/5 PPC or PPC,and Fas expression and apoptosis were positively correlated by relativity analysis. There was no significant correlation between Fas expression and apoptosis in LoVo cells. Conclusions:We could find out hypersensitive drugs and their appropriate dosage according to apoptosis, partly according to Fas expression. The different apoptosis paths between LS174T cells and LoVo cells demonstrate the importance of individualized selection of chemotherapeutic drugs." @default.
- W60751609 created "2016-06-24" @default.
- W60751609 creator A5002725824 @default.
- W60751609 date "2001-01-01" @default.
- W60751609 modified "2023-09-25" @default.
- W60751609 title "Relationship between Fas/FasL expression and apoptosis of colon adenocarcinoma cell lines" @default.
- W60751609 hasPublicationYear "2001" @default.
- W60751609 type Work @default.
- W60751609 sameAs 60751609 @default.
- W60751609 citedByCount "0" @default.
- W60751609 crossrefType "journal-article" @default.
- W60751609 hasAuthorship W60751609A5002725824 @default.
- W60751609 hasConcept C121608353 @default.
- W60751609 hasConcept C1491633281 @default.
- W60751609 hasConcept C153911025 @default.
- W60751609 hasConcept C185592680 @default.
- W60751609 hasConcept C190283241 @default.
- W60751609 hasConcept C2778271344 @default.
- W60751609 hasConcept C2781182431 @default.
- W60751609 hasConcept C31573885 @default.
- W60751609 hasConcept C502942594 @default.
- W60751609 hasConcept C54355233 @default.
- W60751609 hasConcept C552990157 @default.
- W60751609 hasConcept C55493867 @default.
- W60751609 hasConcept C66008609 @default.
- W60751609 hasConcept C81885089 @default.
- W60751609 hasConcept C86803240 @default.
- W60751609 hasConceptScore W60751609C121608353 @default.
- W60751609 hasConceptScore W60751609C1491633281 @default.
- W60751609 hasConceptScore W60751609C153911025 @default.
- W60751609 hasConceptScore W60751609C185592680 @default.
- W60751609 hasConceptScore W60751609C190283241 @default.
- W60751609 hasConceptScore W60751609C2778271344 @default.
- W60751609 hasConceptScore W60751609C2781182431 @default.
- W60751609 hasConceptScore W60751609C31573885 @default.
- W60751609 hasConceptScore W60751609C502942594 @default.
- W60751609 hasConceptScore W60751609C54355233 @default.
- W60751609 hasConceptScore W60751609C552990157 @default.
- W60751609 hasConceptScore W60751609C55493867 @default.
- W60751609 hasConceptScore W60751609C66008609 @default.
- W60751609 hasConceptScore W60751609C81885089 @default.
- W60751609 hasConceptScore W60751609C86803240 @default.
- W60751609 hasLocation W607516091 @default.
- W60751609 hasOpenAccess W60751609 @default.
- W60751609 hasPrimaryLocation W607516091 @default.
- W60751609 hasRelatedWork W2005929804 @default.
- W60751609 hasRelatedWork W2082205783 @default.
- W60751609 hasRelatedWork W2349184282 @default.
- W60751609 hasRelatedWork W2350466793 @default.
- W60751609 hasRelatedWork W2351699834 @default.
- W60751609 hasRelatedWork W2367657642 @default.
- W60751609 hasRelatedWork W2367793383 @default.
- W60751609 hasRelatedWork W2370342628 @default.
- W60751609 hasRelatedWork W2370484755 @default.
- W60751609 hasRelatedWork W2370747971 @default.
- W60751609 hasRelatedWork W2374223939 @default.
- W60751609 hasRelatedWork W2374433015 @default.
- W60751609 hasRelatedWork W2375276999 @default.
- W60751609 hasRelatedWork W2377653201 @default.
- W60751609 hasRelatedWork W2378586824 @default.
- W60751609 hasRelatedWork W2380783647 @default.
- W60751609 hasRelatedWork W2382675427 @default.
- W60751609 hasRelatedWork W2386013660 @default.
- W60751609 hasRelatedWork W2386747963 @default.
- W60751609 hasRelatedWork W2392675299 @default.
- W60751609 isParatext "false" @default.
- W60751609 isRetracted "false" @default.
- W60751609 magId "60751609" @default.
- W60751609 workType "article" @default.