Matches in SemOpenAlex for { <https://semopenalex.org/work/W607553609> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W607553609 abstract "High-dose chemoradiotherapy and allogeneic bone marrow transplantation (BMT) can cure some patients with acute leukemia and lymphoma. However, approximately 50% of patients relapse after BMT and constitute the group with unfavourable prognosis. Results of salvage chemotherapy in these patients are extremely poor [1], so new alternatives have emerged during the past decade in the field of immunotherapy. The efficacy of allogeneic BMT is usually associated with graft versus host disease (GVHD) and especially with graft versus leukemia (GVL) phenomenon that is carried out by donor’s T-lymphocytes [2]. The absence of GVHD in syngeneic and autologous BMT, T-depletion in allogeneic BMT, more intensive GVHD prophylaxis lead to the higher leukemia relapse rate. It was revealed that induction of GVL effect may be independent of GVHD and can be mediated by cyclosporine A, inter-leukin-2 (IL-2), transfusion of donor’s leukocytes [3, 4, 5]. Those approaches are being used in order to prevent or to treat leukemia relapse after bone marrow transplantation that is to say to prolong disease-free survival. The largest report concerning DLI in relapsed BMT patients comprises 82 cases (chronic myeloid leukemia, acute leukemias) and demonstrates encouraging results [6]. This article will briefly summarise our experience in the treatment of relapses after allogeneic BMT with donor’s leukocytes infusions." @default.
- W607553609 created "2016-06-24" @default.
- W607553609 creator A5013516331 @default.
- W607553609 creator A5014421357 @default.
- W607553609 creator A5029401440 @default.
- W607553609 creator A5031734564 @default.
- W607553609 creator A5036801208 @default.
- W607553609 creator A5050028940 @default.
- W607553609 creator A5075559344 @default.
- W607553609 date "1996-01-01" @default.
- W607553609 modified "2023-10-07" @default.
- W607553609 title "Donor Leukocyte Infusions (DLI) in the Treatment of AML Patients Relapsed After Allogeneic Bone Marrow Transplantation" @default.
- W607553609 cites W1808421175 @default.
- W607553609 cites W1975452134 @default.
- W607553609 cites W2028305744 @default.
- W607553609 cites W2150917826 @default.
- W607553609 doi "https://doi.org/10.1007/978-3-642-78907-6_64" @default.
- W607553609 hasPublicationYear "1996" @default.
- W607553609 type Work @default.
- W607553609 sameAs 607553609 @default.
- W607553609 citedByCount "2" @default.
- W607553609 countsByYear W6075536092013 @default.
- W607553609 countsByYear W6075536092014 @default.
- W607553609 crossrefType "book-chapter" @default.
- W607553609 hasAuthorship W607553609A5013516331 @default.
- W607553609 hasAuthorship W607553609A5014421357 @default.
- W607553609 hasAuthorship W607553609A5029401440 @default.
- W607553609 hasAuthorship W607553609A5031734564 @default.
- W607553609 hasAuthorship W607553609A5036801208 @default.
- W607553609 hasAuthorship W607553609A5050028940 @default.
- W607553609 hasAuthorship W607553609A5075559344 @default.
- W607553609 hasConcept C126322002 @default.
- W607553609 hasConcept C143998085 @default.
- W607553609 hasConcept C203014093 @default.
- W607553609 hasConcept C2776694085 @default.
- W607553609 hasConcept C2777701055 @default.
- W607553609 hasConcept C2778461978 @default.
- W607553609 hasConcept C2778729363 @default.
- W607553609 hasConcept C2779338263 @default.
- W607553609 hasConcept C2779695342 @default.
- W607553609 hasConcept C2779972918 @default.
- W607553609 hasConcept C2780007613 @default.
- W607553609 hasConcept C2911091166 @default.
- W607553609 hasConcept C71924100 @default.
- W607553609 hasConcept C8891405 @default.
- W607553609 hasConceptScore W607553609C126322002 @default.
- W607553609 hasConceptScore W607553609C143998085 @default.
- W607553609 hasConceptScore W607553609C203014093 @default.
- W607553609 hasConceptScore W607553609C2776694085 @default.
- W607553609 hasConceptScore W607553609C2777701055 @default.
- W607553609 hasConceptScore W607553609C2778461978 @default.
- W607553609 hasConceptScore W607553609C2778729363 @default.
- W607553609 hasConceptScore W607553609C2779338263 @default.
- W607553609 hasConceptScore W607553609C2779695342 @default.
- W607553609 hasConceptScore W607553609C2779972918 @default.
- W607553609 hasConceptScore W607553609C2780007613 @default.
- W607553609 hasConceptScore W607553609C2911091166 @default.
- W607553609 hasConceptScore W607553609C71924100 @default.
- W607553609 hasConceptScore W607553609C8891405 @default.
- W607553609 hasLocation W6075536091 @default.
- W607553609 hasOpenAccess W607553609 @default.
- W607553609 hasPrimaryLocation W6075536091 @default.
- W607553609 hasRelatedWork W1144468266 @default.
- W607553609 hasRelatedWork W1707184873 @default.
- W607553609 hasRelatedWork W178107838 @default.
- W607553609 hasRelatedWork W2007409729 @default.
- W607553609 hasRelatedWork W2074681088 @default.
- W607553609 hasRelatedWork W2078163947 @default.
- W607553609 hasRelatedWork W2085124551 @default.
- W607553609 hasRelatedWork W2093301069 @default.
- W607553609 hasRelatedWork W2148594391 @default.
- W607553609 hasRelatedWork W2228186361 @default.
- W607553609 hasRelatedWork W2265823874 @default.
- W607553609 hasRelatedWork W2400449391 @default.
- W607553609 hasRelatedWork W2410073476 @default.
- W607553609 hasRelatedWork W2410349996 @default.
- W607553609 hasRelatedWork W2427384465 @default.
- W607553609 hasRelatedWork W2438498684 @default.
- W607553609 hasRelatedWork W2464958785 @default.
- W607553609 hasRelatedWork W2983885694 @default.
- W607553609 hasRelatedWork W2984328697 @default.
- W607553609 hasRelatedWork W88046986 @default.
- W607553609 isParatext "false" @default.
- W607553609 isRetracted "false" @default.
- W607553609 magId "607553609" @default.
- W607553609 workType "book-chapter" @default.