FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W608673451> ?p ?o ?g. }

• W608673451 endingPage "372" @default.
• W608673451 startingPage "367" @default.
• W608673451 abstract "This work initially illustrated the formation mechanism of chiral mesoporous silica (CMS) in a brand new insight named biomimetic synthesis. Three kinds of biomimetic synthesized CMS (B-CMS, including B-CMS1, B-CMS2 and B-CMS3) were prepared using different pH or stirring rate condition, and their characteristics were tested with transmission electron microscope and small angle X-ray diffraction. The model drug indomethacin was loaded into B-CMS and drug loading content was measured using ultraviolet spectroscopy. The result suggested that pH condition influenced energetics of self-assembly process, mainly packing energetics of the surfactant, while stirring rate was the more dominant factor to determine particle length. In application, indomethacin loading content was measured to be 35.3%, 34.8% and 35.1% for indomethacin loaded B-CMS1, indomethacin loaded B-CMS2 and indomethacin loaded B-CMS3. After loading indomethacin into B-CMS carriers, surface area, pore volume and pore diameter of B-CMS carriers were reduced. B-CMS converted crystalline state of indomethacin to amorphous state, leading to the improved indomethacin dissolution. B-CMS1 controlled drug release without burst-release, while B-CMS2 and B-CMS3 released indomethacin faster than B-CMS1, demonstrating that the particle length, the ordered lever of multiple helixes, the curvature degree of helical channels and pore diameter greatly contributed to the release behavior of indomethacin loaded B-CMS." @default.
• W608673451 created "2016-06-24" @default.
• W608673451 creator A5011066587 @default.
• W608673451 creator A5012308001 @default.
• W608673451 creator A5012677271 @default.
• W608673451 creator A5038049942 @default.
• W608673451 creator A5040524739 @default.
• W608673451 creator A5079396055 @default.
• W608673451 date "2015-10-01" @default.
• W608673451 modified "2023-09-27" @default.
• W608673451 title "Biomimetic synthesized chiral mesoporous silica: Structures and controlled release functions as drug carrier" @default.
• W608673451 cites W1590254871 @default.
• W608673451 cites W1967260264 @default.
• W608673451 cites W2007790188 @default.
• W608673451 cites W2009653328 @default.
• W608673451 cites W2012447216 @default.
• W608673451 cites W2017466308 @default.
• W608673451 cites W2020149715 @default.
• W608673451 cites W2021479394 @default.
• W608673451 cites W2027066142 @default.
• W608673451 cites W2033002982 @default.
• W608673451 cites W2038903689 @default.
• W608673451 cites W2046368439 @default.
• W608673451 cites W2051084066 @default.
• W608673451 cites W2060450510 @default.
• W608673451 cites W2075496888 @default.
• W608673451 cites W2081803762 @default.
• W608673451 cites W2083936776 @default.
• W608673451 cites W2084936015 @default.
• W608673451 cites W2089906561 @default.
• W608673451 cites W2106039408 @default.
• W608673451 cites W2120377825 @default.
• W608673451 cites W2124894650 @default.
• W608673451 cites W2129780762 @default.
• W608673451 cites W2135852721 @default.
• W608673451 cites W2169287053 @default.
• W608673451 doi "https://doi.org/10.1016/j.msec.2015.05.039" @default.
• W608673451 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26117767" @default.
• W608673451 hasPublicationYear "2015" @default.
• W608673451 type Work @default.
• W608673451 sameAs 608673451 @default.
• W608673451 citedByCount "38" @default.
• W608673451 countsByYear W6086734512016 @default.
• W608673451 countsByYear W6086734512017 @default.
• W608673451 countsByYear W6086734512018 @default.
• W608673451 countsByYear W6086734512019 @default.
• W608673451 countsByYear W6086734512020 @default.
• W608673451 countsByYear W6086734512021 @default.
• W608673451 countsByYear W6086734512022 @default.
• W608673451 countsByYear W6086734512023 @default.
• W608673451 crossrefType "journal-article" @default.
• W608673451 hasAuthorship W608673451A5011066587 @default.
• W608673451 hasAuthorship W608673451A5012308001 @default.
• W608673451 hasAuthorship W608673451A5012677271 @default.
• W608673451 hasAuthorship W608673451A5038049942 @default.
• W608673451 hasAuthorship W608673451A5040524739 @default.
• W608673451 hasAuthorship W608673451A5079396055 @default.
• W608673451 hasConcept C104779481 @default.
• W608673451 hasConcept C127413603 @default.
• W608673451 hasConcept C146088050 @default.
• W608673451 hasConcept C14631669 @default.
• W608673451 hasConcept C155672457 @default.
• W608673451 hasConcept C159985019 @default.
• W608673451 hasConcept C161790260 @default.
• W608673451 hasConcept C171250308 @default.
• W608673451 hasConcept C178790620 @default.
• W608673451 hasConcept C185592680 @default.
• W608673451 hasConcept C192562407 @default.
• W608673451 hasConcept C26771246 @default.
• W608673451 hasConcept C42360764 @default.
• W608673451 hasConcept C56052488 @default.
• W608673451 hasConcept C8010536 @default.
• W608673451 hasConcept C82776694 @default.
• W608673451 hasConcept C88380143 @default.
• W608673451 hasConceptScore W608673451C104779481 @default.
• W608673451 hasConceptScore W608673451C127413603 @default.
• W608673451 hasConceptScore W608673451C146088050 @default.
• W608673451 hasConceptScore W608673451C14631669 @default.
• W608673451 hasConceptScore W608673451C155672457 @default.
• W608673451 hasConceptScore W608673451C159985019 @default.
• W608673451 hasConceptScore W608673451C161790260 @default.
• W608673451 hasConceptScore W608673451C171250308 @default.
• W608673451 hasConceptScore W608673451C178790620 @default.
• W608673451 hasConceptScore W608673451C185592680 @default.
• W608673451 hasConceptScore W608673451C192562407 @default.
• W608673451 hasConceptScore W608673451C26771246 @default.
• W608673451 hasConceptScore W608673451C42360764 @default.
• W608673451 hasConceptScore W608673451C56052488 @default.
• W608673451 hasConceptScore W608673451C8010536 @default.
• W608673451 hasConceptScore W608673451C82776694 @default.
• W608673451 hasConceptScore W608673451C88380143 @default.
• W608673451 hasFunder F4320321001 @default.
• W608673451 hasLocation W6086734511 @default.
• W608673451 hasLocation W6086734512 @default.
• W608673451 hasOpenAccess W608673451 @default.
• W608673451 hasPrimaryLocation W6086734511 @default.
• W608673451 hasRelatedWork W1861529186 @default.
• W608673451 hasRelatedWork W1964496313 @default.

• next