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- W608908299 abstract "The pressure and velocity fields within a resonant chamber are calculated with a finite element and the linear fluid/structure interaction code ATILA™. This chapter presents a paper, the objective of which is to create a standing wave of pressure strong enough to produce cavitation at the bulk of the fluid and understand the effect of ultrasonic-induced cavitation pressures on the transport of drugs through biological membranes. This chapter investigates the bladder of a frog. An acoustic chamber, which resonates at a desired frequency, can be designed to get controlled cavitation. The acoustic field is produced using a piezoceramic transducer. This transducer is driven by a wave generator through an audio amplifier. The acoustic test chamber can be immersed in the bladder of a frog, which is filled with a mild salt-water solution. The chamber is designed with a system that enables flow circulation. This chapter shows that simulations exist for a complex chamber designed to explore the effects of cavitation on the drug permeability of tissues." @default.
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- W608908299 date "2003-01-01" @default.
- W608908299 modified "2023-09-27" @default.
- W608908299 title "The design of acoustic resonant chambers by numerical simulation" @default.
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- W608908299 doi "https://doi.org/10.1016/b978-008044046-0.50548-0" @default.
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