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- W60916594 abstract "Tetrahydrobiopterin (BH4) has been used for the therapy of BH4-deficient patients. However, BH4 is poorly absorbed from the intestine. The plasma level of biopterin that was reached after oral administration of BH4 to a BH4-deficient patient was reported to be 1–2% of the levels reached after either intravenous or subcutaneous administration1. This poor absorption from the intestine needs a large amount of BH4 for the oral therapy, leading to high costs." @default.
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- W60916594 date "1993-01-01" @default.
- W60916594 modified "2023-09-23" @default.
- W60916594 title "Oral Administration of Liposomally Entrapped Tetrahydrobiopterin" @default.
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- W60916594 doi "https://doi.org/10.1007/978-1-4615-2960-6_55" @default.
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