FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W609760011> ?p ?o ?g. }

• W609760011 endingPage "559" @default.
• W609760011 startingPage "549" @default.
• W609760011 abstract "Proliferation suppression and apoptosis are the prominent characteristics induced by heat stress (HS) in cells, whereas the effects of HS on cell growth (mass accumulation) are unknown. In this study, Lantang swine (an indigenous breed of China) skeletal muscle satellite cells (SCs) were pre-cultured at 37 °C for 24 h. The HS group was subjected to HS at 41 °C, while the control group was maintained at 37 °C. Heat shock protein 70 (HSP70) expression and SC size are significantly increased (P<0.05) by HS, but cell proliferation is suppressed (P<0.05) and apoptosis is induced (P<0.05). HS led to a lower percentage of SCs in the G0/G1 phase (P<0.05) together with a higher percentage of SCs in the S phase (P<0.05). However, the percentage of SCs in the G2/M phase was decreased (P<0.05) at 48 h but then increased (P<0.05) at 72 h with HS. In addition, the phosphorylation ratios of protein kinase b (Akt), ribosomal protein S6 kinase (S6K), and ribosomal protein S6 were increased (P<0.05) by HS. Nevertheless, the phosphorylation ratios of the 4E binding protein 1 and the eukaryotic initiation factor-4E were indistinguishable (P>0.05) from those of the control group. The phosphorylation ratio of the mammalian target of rapamycin (mTOR) (Ser(2448)) increased (P<0.05) within 48 h, and apparent differences were abrogated at 72 h (P>0.05). Moreover, cleaved caspase-3 expression was increased at 72 h (P<0.05). These findings indicate that HS induces apoptosis and disrupts cell cycle distribution to decrease the number of cells. Additionally, HS can promote SC growth via an activated Akt/mTOR/S6K signaling pathway." @default.
• W609760011 created "2016-06-24" @default.
• W609760011 creator A5011055684 @default.
• W609760011 creator A5015259129 @default.
• W609760011 creator A5039699033 @default.
• W609760011 creator A5064330398 @default.
• W609760011 creator A5066306205 @default.
• W609760011 creator A5089739888 @default.
• W609760011 date "2015-05-25" @default.
• W609760011 modified "2023-10-11" @default.
• W609760011 title "Heat stress inhibits proliferation, promotes growth, and induces apoptosis in cultured Lantang swine skeletal muscle satellite cells" @default.
• W609760011 cites W1769448430 @default.
• W609760011 cites W1892015585 @default.
• W609760011 cites W1966062610 @default.
• W609760011 cites W1967026174 @default.
• W609760011 cites W1968210553 @default.
• W609760011 cites W1971400422 @default.
• W609760011 cites W1972078714 @default.
• W609760011 cites W1975827937 @default.
• W609760011 cites W1976049443 @default.
• W609760011 cites W1981254277 @default.
• W609760011 cites W1983009282 @default.
• W609760011 cites W1985235104 @default.
• W609760011 cites W1998852295 @default.
• W609760011 cites W2000336065 @default.
• W609760011 cites W2009390009 @default.
• W609760011 cites W2011963221 @default.
• W609760011 cites W2014719728 @default.
• W609760011 cites W2019470807 @default.
• W609760011 cites W2034329108 @default.
• W609760011 cites W2063509019 @default.
• W609760011 cites W2065801092 @default.
• W609760011 cites W2067407174 @default.
• W609760011 cites W2081961375 @default.
• W609760011 cites W2086338749 @default.
• W609760011 cites W2094757427 @default.
• W609760011 cites W2126685043 @default.
• W609760011 cites W2164462432 @default.
• W609760011 cites W2165113979 @default.
• W609760011 cites W2194940061 @default.
• W609760011 doi "https://doi.org/10.1631/jzus.b1400339" @default.
• W609760011 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4471607" @default.
• W609760011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26055917" @default.
• W609760011 hasPublicationYear "2015" @default.
• W609760011 type Work @default.
• W609760011 sameAs 609760011 @default.
• W609760011 citedByCount "37" @default.
• W609760011 countsByYear W6097600112015 @default.
• W609760011 countsByYear W6097600112016 @default.
• W609760011 countsByYear W6097600112017 @default.
• W609760011 countsByYear W6097600112018 @default.
• W609760011 countsByYear W6097600112019 @default.
• W609760011 countsByYear W6097600112020 @default.
• W609760011 countsByYear W6097600112021 @default.
• W609760011 countsByYear W6097600112022 @default.
• W609760011 countsByYear W6097600112023 @default.
• W609760011 crossrefType "journal-article" @default.
• W609760011 hasAuthorship W609760011A5011055684 @default.
• W609760011 hasAuthorship W609760011A5015259129 @default.
• W609760011 hasAuthorship W609760011A5039699033 @default.
• W609760011 hasAuthorship W609760011A5064330398 @default.
• W609760011 hasAuthorship W609760011A5066306205 @default.
• W609760011 hasAuthorship W609760011A5089739888 @default.
• W609760011 hasBestOaLocation W6097600111 @default.
• W609760011 hasConcept C104202773 @default.
• W609760011 hasConcept C104317684 @default.
• W609760011 hasConcept C11960822 @default.
• W609760011 hasConcept C126322002 @default.
• W609760011 hasConcept C134018914 @default.
• W609760011 hasConcept C153911025 @default.
• W609760011 hasConcept C16685009 @default.
• W609760011 hasConcept C184235292 @default.
• W609760011 hasConcept C185592680 @default.
• W609760011 hasConcept C190283241 @default.
• W609760011 hasConcept C205260736 @default.
• W609760011 hasConcept C2780044377 @default.
• W609760011 hasConcept C2780926556 @default.
• W609760011 hasConcept C55493867 @default.
• W609760011 hasConcept C62112901 @default.
• W609760011 hasConcept C68991219 @default.
• W609760011 hasConcept C71924100 @default.
• W609760011 hasConcept C75217442 @default.
• W609760011 hasConcept C86554907 @default.
• W609760011 hasConcept C86803240 @default.
• W609760011 hasConcept C95444343 @default.
• W609760011 hasConceptScore W609760011C104202773 @default.
• W609760011 hasConceptScore W609760011C104317684 @default.
• W609760011 hasConceptScore W609760011C11960822 @default.
• W609760011 hasConceptScore W609760011C126322002 @default.
• W609760011 hasConceptScore W609760011C134018914 @default.
• W609760011 hasConceptScore W609760011C153911025 @default.
• W609760011 hasConceptScore W609760011C16685009 @default.
• W609760011 hasConceptScore W609760011C184235292 @default.
• W609760011 hasConceptScore W609760011C185592680 @default.
• W609760011 hasConceptScore W609760011C190283241 @default.
• W609760011 hasConceptScore W609760011C205260736 @default.
• W609760011 hasConceptScore W609760011C2780044377 @default.
• W609760011 hasConceptScore W609760011C2780926556 @default.

• next