FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W611036750> ?p ?o ?g. }

• W611036750 endingPage "1488" @default.
• W611036750 startingPage "1481" @default.
• W611036750 abstract "Ischemia/reperfusion (I/R) injury is an inevitable consequence of organ transplantation and a major determinant of patient and graft survival in heart transplantation. Bone marrow-mesenchymal stromal cell (BM-MSC) treatment is a potentially effective cell therapy for cardiac disease. We investigated the effects of intravenous delivery of BM-MSCs in the acute phase post-transplant in a heterotopic heart transplantation (HHT) model associated with I/R injury.Hearts of wild-type Lewis (WT LEW) rats were harvested and transplanted heterotopically into the necks of recipient WT LEW rats. Forty-eight hours after HHT, BM-MSCs were injected intravenously into animals in the experimental group, whereas controls received normal saline (NS).Eight days after BM-MSC injection, fractional shortening of transplanted hearts was significantly higher and left ventricular systolic diameter was lower in the BM-MSC group compared with controls, whereas no differences were found 28 days after infusion. A reduction in ventricular remodeling and cardiac fibrosis was observed by histochemical analysis and confirmed by cardiac magnetic resonance imaging in the BM-MSC group. The perivascular stromal cells' density and the number of capillaries were increased whereas the number of apoptotic cells decreased significantly in transplanted hearts in the BM-MSC group compared with the NS group.We showed early improvement in cardiac function and subsequent enhanced ventricular remodeling, reduced cardiac fibrosis, augmented neo-vascularization and decreased cardiomyocyte apoptosis of the transplanted heart in a heterotopic transplantation model after intravenous infusion of BM-derived MSCs. Our data suggest that clinical studies with BM-MSCs are warranted to understand their effects on cardiac graft and transplant recipient survival." @default.
• W611036750 created "2016-06-24" @default.
• W611036750 creator A5011630694 @default.
• W611036750 creator A5015212635 @default.
• W611036750 creator A5028042700 @default.
• W611036750 creator A5050723566 @default.
• W611036750 creator A5060475589 @default.
• W611036750 creator A5065148163 @default.
• W611036750 creator A5078836143 @default.
• W611036750 date "2015-11-01" @default.
• W611036750 modified "2023-10-06" @default.
• W611036750 title "Mesenchymal stromal cells improve cardiac function and left ventricular remodeling in a heart transplantation model" @default.
• W611036750 cites W1600258010 @default.
• W611036750 cites W1626205173 @default.
• W611036750 cites W1962345831 @default.
• W611036750 cites W1988009177 @default.
• W611036750 cites W1990062396 @default.
• W611036750 cites W2001682169 @default.
• W611036750 cites W2004838611 @default.
• W611036750 cites W2010217891 @default.
• W611036750 cites W2023301282 @default.
• W611036750 cites W2025371271 @default.
• W611036750 cites W2032357416 @default.
• W611036750 cites W2034159130 @default.
• W611036750 cites W2038754539 @default.
• W611036750 cites W2039087506 @default.
• W611036750 cites W2051395985 @default.
• W611036750 cites W2055424631 @default.
• W611036750 cites W2060167203 @default.
• W611036750 cites W2080696419 @default.
• W611036750 cites W2082900428 @default.
• W611036750 cites W2089214984 @default.
• W611036750 cites W2092810335 @default.
• W611036750 cites W2100301825 @default.
• W611036750 cites W2101241187 @default.
• W611036750 cites W2102071079 @default.
• W611036750 cites W2117981319 @default.
• W611036750 cites W2121176039 @default.
• W611036750 cites W2121659762 @default.
• W611036750 cites W2171308531 @default.
• W611036750 cites W2317235122 @default.
• W611036750 cites W2317771222 @default.
• W611036750 cites W2332503922 @default.
• W611036750 cites W2770847249 @default.
• W611036750 cites W28679744 @default.
• W611036750 cites W4239358355 @default.
• W611036750 doi "https://doi.org/10.1016/j.healun.2015.05.008" @default.
• W611036750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26234284" @default.
• W611036750 hasPublicationYear "2015" @default.
• W611036750 type Work @default.
• W611036750 sameAs 611036750 @default.
• W611036750 citedByCount "18" @default.
• W611036750 countsByYear W6110367502016 @default.
• W611036750 countsByYear W6110367502017 @default.
• W611036750 countsByYear W6110367502018 @default.
• W611036750 countsByYear W6110367502019 @default.
• W611036750 countsByYear W6110367502020 @default.
• W611036750 countsByYear W6110367502021 @default.
• W611036750 countsByYear W6110367502023 @default.
• W611036750 crossrefType "journal-article" @default.
• W611036750 hasAuthorship W611036750A5011630694 @default.
• W611036750 hasAuthorship W611036750A5015212635 @default.
• W611036750 hasAuthorship W611036750A5028042700 @default.
• W611036750 hasAuthorship W611036750A5050723566 @default.
• W611036750 hasAuthorship W611036750A5060475589 @default.
• W611036750 hasAuthorship W611036750A5065148163 @default.
• W611036750 hasAuthorship W611036750A5078836143 @default.
• W611036750 hasBestOaLocation W6110367502 @default.
• W611036750 hasConcept C111566952 @default.
• W611036750 hasConcept C126322002 @default.
• W611036750 hasConcept C142724271 @default.
• W611036750 hasConcept C164705383 @default.
• W611036750 hasConcept C16930146 @default.
• W611036750 hasConcept C198826908 @default.
• W611036750 hasConcept C2777420927 @default.
• W611036750 hasConcept C2778198053 @default.
• W611036750 hasConcept C2778849806 @default.
• W611036750 hasConcept C2779537366 @default.
• W611036750 hasConcept C2780007613 @default.
• W611036750 hasConcept C2780559512 @default.
• W611036750 hasConcept C2911091166 @default.
• W611036750 hasConcept C71924100 @default.
• W611036750 hasConceptScore W611036750C111566952 @default.
• W611036750 hasConceptScore W611036750C126322002 @default.
• W611036750 hasConceptScore W611036750C142724271 @default.
• W611036750 hasConceptScore W611036750C164705383 @default.
• W611036750 hasConceptScore W611036750C16930146 @default.
• W611036750 hasConceptScore W611036750C198826908 @default.
• W611036750 hasConceptScore W611036750C2777420927 @default.
• W611036750 hasConceptScore W611036750C2778198053 @default.
• W611036750 hasConceptScore W611036750C2778849806 @default.
• W611036750 hasConceptScore W611036750C2779537366 @default.
• W611036750 hasConceptScore W611036750C2780007613 @default.
• W611036750 hasConceptScore W611036750C2780559512 @default.
• W611036750 hasConceptScore W611036750C2911091166 @default.
• W611036750 hasConceptScore W611036750C71924100 @default.
• W611036750 hasIssue "11" @default.
• W611036750 hasLocation W6110367501 @default.

• next