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- W611757052 abstract "Covalent attachment of ubiquitin, a process termed ubiquitination, affects the location, function, and stability of modified proteins. Significant advances have been made in building synthetic ubiquitin-protein conjugates that can be used to investigate how ubiquitin regulates diverse biological processes. Herein we describe recent advances and discuss how chemical methods have been implemented to address the molecular underpinnings of ubiquitin-dependent cellular signaling." @default.
- W611757052 created "2016-06-24" @default.
- W611757052 creator A5016706111 @default.
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- W611757052 date "2015-10-01" @default.
- W611757052 modified "2023-09-24" @default.
- W611757052 title "Peeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin–protein conjugates" @default.
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- W611757052 doi "https://doi.org/10.1016/j.cbpa.2015.06.001" @default.
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