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- W61226137 abstract "Biocompatible fluorocarbon emulsions can enhance ultrasound echogenicity (ECHO) of tissue and provide abundant fluorine for magnetic resonance (MR) imaging. The authors substituted 50 per cent of the blood volume of anesthetized swine with fluorocarbon emulsion (FC-43). Heart regions were made permanently or transiently ischemic for up to 4 h. Serial 2-D echocardiograms were taken and FC-43 content in tissue was assessed by 19-F MR spectroscopy. Ischemic and normal regions held comparable FC-43 (2-4 ..mu..mole/g) after 4h without ECHI differences or enhancement. Transiently ischemic tissue accumulated FC-43 to 20 times normal and ECHO enhanced rapidly. Thus, discrimination between normal, eschemic and reperfused tissues using both ultrasound and MR imaging techniques is aided by fluorocarbon emulsions." @default.
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- W61226137 date "1987-01-01" @default.
- W61226137 modified "2023-09-27" @default.
- W61226137 title "Discrimination of normal, ischemic, and reperfused tissue by ultrasound and magnetic resonance aided by fluorocarbons" @default.
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