Matches in SemOpenAlex for { <https://semopenalex.org/work/W615087116> ?p ?o ?g. }
- W615087116 endingPage "135" @default.
- W615087116 startingPage "128" @default.
- W615087116 abstract "Homosexual men show a 2-4 higher risk to suffer anxiety in comparison with heterosexuals. It is unknown if biological factors collaborate to increase such incidence. Fluoxetine produces differential brain activation in homosexuals as compared with heterosexuals, suggesting that it may produce a divergent behavioral effect dependant on sex-preference. The first aim was to evaluate experimental anxiety in male rats that show same-sex preference in the elevated plus maze (EPM). The second goal explored the putative differential effect of fluoxetine (10mg/kg) in male rats with female and same-sex preference in the EPM. To induce same-sex preference males were prenatally treated with letrozole (0.56μg/kg, 10-20 gestation days), while controls were males prenatally treated with letrozole that retain female-preference or which mothers received oil. In both groups we found animals with male preference, but the proportion was higher in males that prenatally received letrozole (10 vs. 27%). Males with same-sex preference spent less time and showed lower number of entries to the open arms of the EPM than males that prefer females, regardless of the prenatal treatment. In males with female preference, fluoxetine reduced the time spent and number of entries to the open arms that was absent in males with same-sex preference. These data suggest that biological factors contribute to the high levels of anxiety in subjects with same-sex preference and that fluoxetine in men may produce a divergent action depending on sexual orientation." @default.
- W615087116 created "2016-06-24" @default.
- W615087116 creator A5006950916 @default.
- W615087116 creator A5038258986 @default.
- W615087116 creator A5060627874 @default.
- W615087116 creator A5087749286 @default.
- W615087116 date "2015-08-01" @default.
- W615087116 modified "2023-10-16" @default.
- W615087116 title "Male rats with same sex preference show high experimental anxiety and lack of anxiogenic-like effect of fluoxetine in the plus maze test" @default.
- W615087116 cites W12383193 @default.
- W615087116 cites W142084402 @default.
- W615087116 cites W1511964200 @default.
- W615087116 cites W1963759816 @default.
- W615087116 cites W1966964201 @default.
- W615087116 cites W1967421959 @default.
- W615087116 cites W1976154921 @default.
- W615087116 cites W1979521621 @default.
- W615087116 cites W1980919287 @default.
- W615087116 cites W1984130440 @default.
- W615087116 cites W1997630605 @default.
- W615087116 cites W2002836739 @default.
- W615087116 cites W2007155895 @default.
- W615087116 cites W2009100827 @default.
- W615087116 cites W2013250524 @default.
- W615087116 cites W2017436597 @default.
- W615087116 cites W2018286553 @default.
- W615087116 cites W2021025118 @default.
- W615087116 cites W2026081258 @default.
- W615087116 cites W2027540433 @default.
- W615087116 cites W2030401640 @default.
- W615087116 cites W2035221267 @default.
- W615087116 cites W2036245134 @default.
- W615087116 cites W2039634102 @default.
- W615087116 cites W2040202195 @default.
- W615087116 cites W2041561931 @default.
- W615087116 cites W2043730377 @default.
- W615087116 cites W2044201957 @default.
- W615087116 cites W2044297059 @default.
- W615087116 cites W2045773196 @default.
- W615087116 cites W2051979792 @default.
- W615087116 cites W2052318755 @default.
- W615087116 cites W2055586160 @default.
- W615087116 cites W2055745997 @default.
- W615087116 cites W2059297425 @default.
- W615087116 cites W2061054421 @default.
- W615087116 cites W2066770086 @default.
- W615087116 cites W2069192879 @default.
- W615087116 cites W2072867057 @default.
- W615087116 cites W2077621719 @default.
- W615087116 cites W2077837140 @default.
- W615087116 cites W2079555774 @default.
- W615087116 cites W2091793491 @default.
- W615087116 cites W2092465482 @default.
- W615087116 cites W2092953670 @default.
- W615087116 cites W2101506937 @default.
- W615087116 cites W2101974080 @default.
- W615087116 cites W2121667107 @default.
- W615087116 cites W2122062108 @default.
- W615087116 cites W2123310672 @default.
- W615087116 cites W2125568653 @default.
- W615087116 cites W2131830842 @default.
- W615087116 cites W2138581472 @default.
- W615087116 cites W2140107414 @default.
- W615087116 cites W2146694611 @default.
- W615087116 cites W2148256999 @default.
- W615087116 cites W2161678767 @default.
- W615087116 cites W2169358550 @default.
- W615087116 cites W2801086494 @default.
- W615087116 cites W4244851348 @default.
- W615087116 doi "https://doi.org/10.1016/j.pbb.2015.05.017" @default.
- W615087116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26044966" @default.
- W615087116 hasPublicationYear "2015" @default.
- W615087116 type Work @default.
- W615087116 sameAs 615087116 @default.
- W615087116 citedByCount "14" @default.
- W615087116 countsByYear W6150871162017 @default.
- W615087116 countsByYear W6150871162018 @default.
- W615087116 countsByYear W6150871162019 @default.
- W615087116 countsByYear W6150871162020 @default.
- W615087116 countsByYear W6150871162021 @default.
- W615087116 countsByYear W6150871162022 @default.
- W615087116 countsByYear W6150871162023 @default.
- W615087116 crossrefType "journal-article" @default.
- W615087116 hasAuthorship W615087116A5006950916 @default.
- W615087116 hasAuthorship W615087116A5038258986 @default.
- W615087116 hasAuthorship W615087116A5060627874 @default.
- W615087116 hasAuthorship W615087116A5087749286 @default.
- W615087116 hasConcept C118552586 @default.
- W615087116 hasConcept C126322002 @default.
- W615087116 hasConcept C138496976 @default.
- W615087116 hasConcept C15744967 @default.
- W615087116 hasConcept C162324750 @default.
- W615087116 hasConcept C170493617 @default.
- W615087116 hasConcept C173586616 @default.
- W615087116 hasConcept C175444787 @default.
- W615087116 hasConcept C205044023 @default.
- W615087116 hasConcept C2775864247 @default.
- W615087116 hasConcept C2776134451 @default.