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- W61529835 abstract "The authors have used EDTA-based metal chelate buffer system to control the speciation of Cd in seawater in order to examine the relationships between free Cd ion activity (Cd{sup +2}) and Cd bioavailability, accumulation and toxicity in the errant polychaete, Neanthes arenceodentata. At external concentrations of (Cd{sup +2}) below 10{sup {minus}10} M, the accumulated dose of Cd in the organism at steady state condition is proportional to the concentrations of metal in the media. An order of magnitude increase in total body load of Cd is observed for each order of magnitude increase in (Cd{sup +2}) in the seawater. At (Cd{sup +2}) greater than 10{sup {minus}9} M, however, the accumulation of Cd by the organisms exceeded proportionality relative to the (Cd{sup +2}) in the seawater. Subcellular fractionation studies show that this increase in accumulation in total body load is due to the combined effects of increased metal accumulation in two cytosolic ligand pools. At 10{sup {minus}9} M (Cd{sup +2}), there is elevated levels of Cd in the metallothionein pool (MT) which appears to reflect induction of the protein. At Cd{sup +2} higher than 10{sup {minus}8} M, there is no further accumulation of Cd on MT, but there is a dramaticmore » increase of Cd in the low molecular weight ligand pool.« less" @default.
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- W61529835 date "1988-09-01" @default.
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- W61529835 title "Low molecular weight metal ligands: Indicators of metal-induced stress" @default.
- W61529835 hasPublicationYear "1988" @default.
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