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• W615668923 abstract "Acid-related disease (ARD) is a term used to describe a range of conditions in which acid is involved in the generation of symptoms and/or complications. Two of the most common ARDs are gastro-esophageal reflux disease (GERD) and peptic ulcer disease (PUD). PPIs are today regarded as the gold standard in the treatment of both symptoms and mucosal injury in patients with GERD as well as for prevention and acute treatment of PUD. Since the PPIs were introduced in the late 1980-ies there has been a sharp increase in the usage in the Western world. Although this increase coincides with the GERD epidemic it has also led to concerns related to PPI over-utilization, with high costs and associated long-term side-effects. In contrast, there is an apparent underutilization of PPIs as gastroprotective therapy in patients at elevated risk of PUD when taking certain medication. Observational studies have also suggested that the clinical efficacy of PPI therapy may be reduced because of poor adherence. Despite PPIs being among the most widely used prescription drugs there are scarce data on the natural utilization patterns of PPIs. Furthermore the implementation of various cost-containment programs, imposing restrictions on PPI prescriptions, has rarely been evaluated in a systematic manner. A much debated issue is whether the diagnosis and initial treatment of GERD, after excluding patients with an indication for prompt esophagogastroduodenoscopy (EGD) (alarm symptoms or age above 50 years), should be based on symptoms or if EGD shall be performed upfront. A number of patient reported questionnaires have been developed in order to facilitate the symptom-based diagnosis of GERD. In the first study a validation of a questionnaire (GerdQ) as a diagnostic tool for GERD was performed. A GerdQ cutoff score ≥9 gave the best balance between sensitivity, 66% (95% CI 58-74%) and specificity, 64% (95% CI 41-83%), for GERD." @default.
• W615668923 created "2016-06-24" @default.
• W615668923 creator A5043082194 @default.
• W615668923 date "2013-06-18" @default.
• W615668923 modified "2023-09-23" @default.
• W615668923 title "Proton pump inhibitors in acid-related diseases. Issues in diagnosis, treatment and outcome" @default.
• W615668923 cites W130266232 @default.
• W615668923 cites W1480756439 @default.
• W615668923 cites W1482976729 @default.
• W615668923 cites W1489584806 @default.
• W615668923 cites W1494777045 @default.
• W615668923 cites W1521643570 @default.
• W615668923 cites W1557836391 @default.
• W615668923 cites W1572605277 @default.
• W615668923 cites W1586062353 @default.
• W615668923 cites W1601084717 @default.
• W615668923 cites W1836437033 @default.
• W615668923 cites W1905117635 @default.
• W615668923 cites W1967276177 @default.
• W615668923 cites W1967501741 @default.
• W615668923 cites W1969462200 @default.
• W615668923 cites W1972368489 @default.
• W615668923 cites W1973371445 @default.
• W615668923 cites W1975454616 @default.
• W615668923 cites W1977256753 @default.
• W615668923 cites W1978032646 @default.
• W615668923 cites W1981816788 @default.
• W615668923 cites W1985431120 @default.
• W615668923 cites W1988145586 @default.
• W615668923 cites W1989188121 @default.
• W615668923 cites W1990824360 @default.
• W615668923 cites W1995820163 @default.
• W615668923 cites W1996674377 @default.
• W615668923 cites W1997299736 @default.
• W615668923 cites W1999411645 @default.
• W615668923 cites W2000865109 @default.
• W615668923 cites W2001112929 @default.
• W615668923 cites W2001350224 @default.
• W615668923 cites W2004065292 @default.
• W615668923 cites W2007567412 @default.
• W615668923 cites W2008373894 @default.
• W615668923 cites W2009519877 @default.
• W615668923 cites W2009548090 @default.
• W615668923 cites W2012920835 @default.
• W615668923 cites W2014742673 @default.
• W615668923 cites W2015180374 @default.
• W615668923 cites W2015698186 @default.
• W615668923 cites W2017410957 @default.
• W615668923 cites W2017818343 @default.
• W615668923 cites W2019203561 @default.
• W615668923 cites W2022124951 @default.
• W615668923 cites W2024938998 @default.
• W615668923 cites W2025802509 @default.
• W615668923 cites W2026639275 @default.
• W615668923 cites W2027698993 @default.
• W615668923 cites W2029880604 @default.
• W615668923 cites W2030635648 @default.
• W615668923 cites W2032521184 @default.
• W615668923 cites W2032970352 @default.
• W615668923 cites W2036222272 @default.
• W615668923 cites W2037247705 @default.
• W615668923 cites W2040177686 @default.
• W615668923 cites W2041998517 @default.
• W615668923 cites W2042158053 @default.
• W615668923 cites W2043183557 @default.
• W615668923 cites W2043396343 @default.
• W615668923 cites W2044246400 @default.
• W615668923 cites W2045276152 @default.
• W615668923 cites W2045917115 @default.
• W615668923 cites W2047844017 @default.
• W615668923 cites W2048532076 @default.
• W615668923 cites W2048722122 @default.
• W615668923 cites W2051048375 @default.
• W615668923 cites W2051715529 @default.
• W615668923 cites W2052703526 @default.
• W615668923 cites W205410055 @default.
• W615668923 cites W2054883739 @default.
• W615668923 cites W2055394727 @default.
• W615668923 cites W2055521278 @default.
• W615668923 cites W2058360584 @default.
• W615668923 cites W2060718379 @default.
• W615668923 cites W2060853834 @default.
• W615668923 cites W2063844762 @default.
• W615668923 cites W2064368339 @default.
• W615668923 cites W2066181948 @default.
• W615668923 cites W2073859326 @default.
• W615668923 cites W2076718515 @default.
• W615668923 cites W2082867546 @default.
• W615668923 cites W2083325871 @default.
• W615668923 cites W2084264352 @default.
• W615668923 cites W2084863173 @default.
• W615668923 cites W2085116012 @default.
• W615668923 cites W2085393332 @default.
• W615668923 cites W2086960999 @default.
• W615668923 cites W2094240522 @default.
• W615668923 cites W2096874183 @default.
• W615668923 cites W2098360247 @default.
• W615668923 cites W2099999179 @default.
• W615668923 cites W2104379105 @default.
• W615668923 cites W2105606912 @default.

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