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- W61606023 abstract "Acute lung injury (ALI) is caused by multiple factors, leading to increased permeability of the alveolo-capillary membrane and derangement of the surfactant system [1]. One of the causes of the disturbed surfactant system is the inactivation of endogenous surfactant by plasma-derived proteins, which leads to alveolar instability and, in turn, to an increase in hydrostatic forces favoring pulmonary edema (for review see [2]). Apparently, after the initial insult to the lung, the surfactant system is responsible for further pathophysiological changes and a vicious circle is set in action, finally resulting in the failure of the lung as a gas-exchange organ." @default.
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- W61606023 date "1995-01-01" @default.
- W61606023 modified "2023-09-24" @default.
- W61606023 title "Surfactant Therapy in Respiratory Failure" @default.
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