FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W61639876> ?p ?o ?g. }

• W61639876 endingPage "1538" @default.
• W61639876 startingPage "1529" @default.
• W61639876 abstract "This study sought to assess the effect of angiotensin-converting enzyme (ACE) inhibitors and beta-blockers on all-cause mortality in patients with left ventricular (LV) systolic dysfunction according to gender, race, and the presence of diabetes. Major randomized clinical trials have established that ACE inhibitors and beta-blockers have life-saving benefits in patients with LV systolic dysfunction. Most patients enrolled in these trials were Caucasian men. Whether an equal effect is achieved in women, non-Caucasians, and patients with major comorbidities has not been established. The authors performed a meta-analysis of published and individual patient data from the 12 largest randomized clinical trials of ACE inhibitors and beta-blockers to produce random effects estimates of mortality for subgroups. Data support beneficial reductions in all-cause mortality for the use of beta-blockers in men and women, the use of ACE inhibitors and some beta-blockers in black and white patients, and the use of ACE inhibitors and beta-blockers in patients with or without diabetes. Women with symptomatic LV systolic dysfunction probably benefit from ACE inhibitors, but women with asymptomatic LV systolic dysfunction may not have reduced mortality when treated with ACE inhibitors (pooled relative risk = 0.96; 95% confidence interval: 0.75 to 1.22). The pooled estimate of three beta-blocker studies supports a beneficial effect in black patients with heart failure, but one study assessing bucindolol reported a nonsignificant increase in mortality. Angiotensin-converting enzyme inhibitors and beta-blockers provide life-saving benefits in most of the subpopulations assessed. Women with asymptomatic LV systolic dysfunction may not achieve a mortality benefit when treated with ACE inhibitors." @default.
• W61639876 created "2016-06-24" @default.
• W61639876 creator A5008535622 @default.
• W61639876 creator A5021094428 @default.
• W61639876 creator A5021215061 @default.
• W61639876 creator A5027045893 @default.
• W61639876 creator A5029257839 @default.
• W61639876 creator A5040563784 @default.
• W61639876 creator A5050021922 @default.
• W61639876 creator A5051961415 @default.
• W61639876 creator A5052362377 @default.
• W61639876 creator A5054626427 @default.
• W61639876 creator A5055759582 @default.
• W61639876 creator A5062229327 @default.
• W61639876 creator A5064906147 @default.
• W61639876 creator A5072295474 @default.
• W61639876 creator A5078221253 @default.
• W61639876 date "2003-05-01" @default.
• W61639876 modified "2023-10-01" @default.
• W61639876 title "Efficacy of angiotensin-converting enzyme inhibitors and beta-blockers in the management of left ventricular systolic dysfunction according to race, gender, and diabetic status" @default.
• W61639876 cites W180946569 @default.
• W61639876 cites W1964435302 @default.
• W61639876 cites W1981498546 @default.
• W61639876 cites W1987016701 @default.
• W61639876 cites W1999030245 @default.
• W61639876 cites W2008904760 @default.
• W61639876 cites W2070568974 @default.
• W61639876 cites W2082096722 @default.
• W61639876 cites W2092266587 @default.
• W61639876 cites W2107328434 @default.
• W61639876 cites W2110103927 @default.
• W61639876 cites W2157823046 @default.
• W61639876 cites W2296998040 @default.
• W61639876 cites W2312388685 @default.
• W61639876 cites W2318174853 @default.
• W61639876 cites W2323549932 @default.
• W61639876 cites W2326354230 @default.
• W61639876 cites W2326508838 @default.
• W61639876 cites W2333113037 @default.
• W61639876 cites W2336619635 @default.
• W61639876 cites W2469805673 @default.
• W61639876 cites W2585382523 @default.
• W61639876 cites W2998034180 @default.
• W61639876 cites W3023522280 @default.
• W61639876 cites W4210834519 @default.
• W61639876 cites W4245244523 @default.
• W61639876 cites W52877415 @default.
• W61639876 doi "https://doi.org/10.1016/s0735-1097(03)00262-6" @default.
• W61639876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12742294" @default.
• W61639876 hasPublicationYear "2003" @default.
• W61639876 type Work @default.
• W61639876 sameAs 61639876 @default.
• W61639876 citedByCount "462" @default.
• W61639876 countsByYear W616398762012 @default.
• W61639876 countsByYear W616398762013 @default.
• W61639876 countsByYear W616398762014 @default.
• W61639876 countsByYear W616398762015 @default.
• W61639876 countsByYear W616398762016 @default.
• W61639876 countsByYear W616398762017 @default.
• W61639876 countsByYear W616398762018 @default.
• W61639876 countsByYear W616398762019 @default.
• W61639876 countsByYear W616398762020 @default.
• W61639876 countsByYear W616398762021 @default.
• W61639876 countsByYear W616398762022 @default.
• W61639876 countsByYear W616398762023 @default.
• W61639876 crossrefType "journal-article" @default.
• W61639876 hasAuthorship W61639876A5008535622 @default.
• W61639876 hasAuthorship W61639876A5021094428 @default.
• W61639876 hasAuthorship W61639876A5021215061 @default.
• W61639876 hasAuthorship W61639876A5027045893 @default.
• W61639876 hasAuthorship W61639876A5029257839 @default.
• W61639876 hasAuthorship W61639876A5040563784 @default.
• W61639876 hasAuthorship W61639876A5050021922 @default.
• W61639876 hasAuthorship W61639876A5051961415 @default.
• W61639876 hasAuthorship W61639876A5052362377 @default.
• W61639876 hasAuthorship W61639876A5054626427 @default.
• W61639876 hasAuthorship W61639876A5055759582 @default.
• W61639876 hasAuthorship W61639876A5062229327 @default.
• W61639876 hasAuthorship W61639876A5064906147 @default.
• W61639876 hasAuthorship W61639876A5072295474 @default.
• W61639876 hasAuthorship W61639876A5078221253 @default.
• W61639876 hasBestOaLocation W616398761 @default.
• W61639876 hasConcept C126322002 @default.
• W61639876 hasConcept C134018914 @default.
• W61639876 hasConcept C164705383 @default.
• W61639876 hasConcept C168563851 @default.
• W61639876 hasConcept C27016395 @default.
• W61639876 hasConcept C2777910003 @default.
• W61639876 hasConcept C2778198053 @default.
• W61639876 hasConcept C2778742482 @default.
• W61639876 hasConcept C2779611605 @default.
• W61639876 hasConcept C555293320 @default.
• W61639876 hasConcept C71924100 @default.
• W61639876 hasConcept C84393581 @default.
• W61639876 hasConceptScore W61639876C126322002 @default.
• W61639876 hasConceptScore W61639876C134018914 @default.
• W61639876 hasConceptScore W61639876C164705383 @default.
• W61639876 hasConceptScore W61639876C168563851 @default.

• next