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• W61653762 abstract "This chapter reviews the role of Magnetic Resonance (MR) imaging in prostate cancer with emphasis on functional imaging techniques and roles in focal therapy. Multiparametric MR imaging sequences applied for prostate cancer imaging include T2-weighted MR, proton MR spectroscopic imaging, diffusion-weighted imaging, dynamic contrast-enhanced MR, and quantitative T2-weighted imaging. These techniques provide information on independent characteristics of normal and cancerous prostate tissue, including normal/abnormal ductal morphology, concentrations of metabolites relevant to prostate cancer, water diffusion rates which are affected by cellularity, blood flow rates and volumes and therefore vascularity, and quantitative morphology, respectively. The information provided by these independent MR imaging methods can be used to determine the presence and location of prostate cancers with high sensitivity and specificity. Prostate MRI can be applied to diagnosing prostate cancer, predicting organ-confined prostate cancer, localization of intra-glandular prostate cancer, and estimation of intra-glandular prostate cancer volume. It has been applied to MR directed transrectal ultrasound-guided biopsy, direct MR-guided biopsy, MR-transrectal ultrasound fusion biopsy, and MR-guided focal therapy. The chapter describes what is known about the potential for combining these imaging techniques to improve selection, guidance, and subsequent monitoring of the effectiveness of focal therapy." @default.
• W61653762 created "2016-06-24" @default.
• W61653762 creator A5003321146 @default.
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• W61653762 date "2012-11-03" @default.
• W61653762 modified "2023-09-27" @default.
• W61653762 title "Multiparametric Magnetic Resonance Imaging Approaches in Focal Prostate Cancer Therapy" @default.
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