FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W616713952> ?p ?o ?g. }

• W616713952 endingPage "574" @default.
• W616713952 startingPage "564" @default.
• W616713952 abstract "The cross-sectional study investigated the impact of chronic low level arsenic (As) exposure (11-50μg/L) on CD14 expression and other inflammatory responses in rural women of West Bengal enrolled from control (As level <10μg/L; N, 131) and exposed area (As level 11-50μg/L, N, 142). Atomic absorption spectroscopy revealed that As level in groundwater was higher in endemic areas (22.93±10. 1 vs. 1.61±0.15, P<0.0001) and showed a positive correlation [Pearsons r, 0.9281; 95% confidence interval, 0.8192-0.9724] with As content in nails of the exposed women. Flow cytometric analysis showed that CD 14 expression on monocytes was significantly higher (P<0.001) in exposed women and positively correlated with groundwater As [Pearsons r, 0.9191; 95% confidence interval, 0.7584-0.9745]. Leucocytes and airway cells of As exposed women exhibited up regulation of an inflammatory mediator, tumor necrosis factor-α (TNF-α) and transcription factor, nuclear factor-κB (NF-κB) (P<0.0001). Plasma pro inflammatory cytokines like - TNF-α, interleukins (ILs) - IL-6, IL-8, IL-12 were elevated whereas anti-inflammatory cytokine IL-10 was depleted in the exposed women. Sputa of the exposed women had elevated activity of inflammatory markers - MMP-2 and MMP-9 whereas sera were observed with only increased activity of MMP-9. Airway cells of the exposed women had exacerbated DNA damage than control. Level of oxidative DNA adducts like 8-hydroxy-2'-deoxyguanosine (8OHdG) were also enhanced in plasma of exposed women. Therefore it might be indicated that low level As exposure elicited a pro-inflammatory profile which might have been contributed in part by CD14 expressing monocytes and prolong persistence of pulmonary and systemic inflammation might have promoted oxidative DNA damage in the rural women." @default.
• W616713952 created "2016-06-24" @default.
• W616713952 creator A5019497899 @default.
• W616713952 creator A5054778252 @default.
• W616713952 creator A5064527697 @default.
• W616713952 date "2015-08-01" @default.
• W616713952 modified "2023-10-13" @default.
• W616713952 title "Chronic low level arsenic exposure evokes inflammatory responses and DNA damage" @default.
• W616713952 cites W1550722396 @default.
• W616713952 cites W1574848475 @default.
• W616713952 cites W1652069479 @default.
• W616713952 cites W1775749144 @default.
• W616713952 cites W1965037168 @default.
• W616713952 cites W1966973738 @default.
• W616713952 cites W1968388033 @default.
• W616713952 cites W1972033007 @default.
• W616713952 cites W1973028149 @default.
• W616713952 cites W1980504504 @default.
• W616713952 cites W1981093951 @default.
• W616713952 cites W1984378291 @default.
• W616713952 cites W1988449390 @default.
• W616713952 cites W1989404875 @default.
• W616713952 cites W2004465286 @default.
• W616713952 cites W2008311655 @default.
• W616713952 cites W2020676344 @default.
• W616713952 cites W2021614328 @default.
• W616713952 cites W2031214198 @default.
• W616713952 cites W2031913204 @default.
• W616713952 cites W2038634709 @default.
• W616713952 cites W2042645986 @default.
• W616713952 cites W2044905143 @default.
• W616713952 cites W2045525839 @default.
• W616713952 cites W2048704934 @default.
• W616713952 cites W2051946033 @default.
• W616713952 cites W2052495169 @default.
• W616713952 cites W2055667618 @default.
• W616713952 cites W2056843357 @default.
• W616713952 cites W2060198845 @default.
• W616713952 cites W2060647682 @default.
• W616713952 cites W2062445195 @default.
• W616713952 cites W2062721793 @default.
• W616713952 cites W2067486887 @default.
• W616713952 cites W2073272200 @default.
• W616713952 cites W2087300676 @default.
• W616713952 cites W2090684755 @default.
• W616713952 cites W2092629964 @default.
• W616713952 cites W2094817906 @default.
• W616713952 cites W2094908805 @default.
• W616713952 cites W2099501408 @default.
• W616713952 cites W2112675066 @default.
• W616713952 cites W2114245800 @default.
• W616713952 cites W2117692326 @default.
• W616713952 cites W2117780076 @default.
• W616713952 cites W2133001264 @default.
• W616713952 cites W2140711005 @default.
• W616713952 cites W2141854216 @default.
• W616713952 cites W2150076336 @default.
• W616713952 cites W2151639536 @default.
• W616713952 cites W2159069239 @default.
• W616713952 cites W2161552991 @default.
• W616713952 cites W2161852451 @default.
• W616713952 cites W2162185805 @default.
• W616713952 cites W2168739412 @default.
• W616713952 cites W2171007292 @default.
• W616713952 cites W2320889530 @default.
• W616713952 cites W2335925695 @default.
• W616713952 doi "https://doi.org/10.1016/j.ijheh.2015.06.003" @default.
• W616713952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26118750" @default.
• W616713952 hasPublicationYear "2015" @default.
• W616713952 type Work @default.
• W616713952 sameAs 616713952 @default.
• W616713952 citedByCount "61" @default.
• W616713952 countsByYear W6167139522016 @default.
• W616713952 countsByYear W6167139522017 @default.
• W616713952 countsByYear W6167139522018 @default.
• W616713952 countsByYear W6167139522019 @default.
• W616713952 countsByYear W6167139522020 @default.
• W616713952 countsByYear W6167139522021 @default.
• W616713952 countsByYear W6167139522022 @default.
• W616713952 countsByYear W6167139522023 @default.
• W616713952 crossrefType "journal-article" @default.
• W616713952 hasAuthorship W616713952A5019497899 @default.
• W616713952 hasAuthorship W616713952A5054778252 @default.
• W616713952 hasAuthorship W616713952A5064527697 @default.
• W616713952 hasConcept C11988809 @default.
• W616713952 hasConcept C126322002 @default.
• W616713952 hasConcept C134018914 @default.
• W616713952 hasConcept C143425029 @default.
• W616713952 hasConcept C17991360 @default.
• W616713952 hasConcept C185592680 @default.
• W616713952 hasConcept C203014093 @default.
• W616713952 hasConcept C2776151105 @default.
• W616713952 hasConcept C2776914184 @default.
• W616713952 hasConcept C2778513237 @default.
• W616713952 hasConcept C2778690821 @default.
• W616713952 hasConcept C552990157 @default.
• W616713952 hasConcept C55493867 @default.
• W616713952 hasConcept C71924100 @default.

• next