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- W617456472 abstract "目的通过检测细菌性和病毒性感染患儿血清中触珠蛋白(haptoglobin,HPT)、α1-酸性糖蛋白(α1 acid glycoprotein,AAG)和C反应蛋白(C-reactive protein,CRP)水平,探讨其对患儿细菌性和病毒性感染的鉴别诊断价值。方法检测64例细菌性感染患儿、64例病毒性感染患儿急性期血清及31例正常对照组患儿血清中HPT、AAG、CRP水平。比较各炎症指标的灵敏度、特异度、阳性预测值、阴性预测值和约登指数,评价它们对细菌感染和病毒感染的早期诊断价值。结果(1)以HPT≥2g/L,AAG≥2g/L,CRP≥10mg/L为阳性标准,3指标对诊断细菌性和病毒性感染的灵敏度分别为82.82%、42.19%、98.44%;(2)细菌感染组和病毒感染组比较HPT[(2.70±0.99)g/L vs(1.42±0.75)g/L]、AAG[(0.91±0.38)g/L vs(0.30±0.08)g/L]、CRP[(6.40±0.89)mg/L vs(1.38±0.80)mg/L]水平显著升高(P〈0.05,P〈0.01);细菌感染组与正常对照组比较亦显著升高(P〈0.05,P〈0.01);而病毒感染组和正常对照组比较,差异无统计学意义(P〉0.05)。结论血清中HPT、AAG和CRP水平检测对患儿细菌性与病毒性感染的鉴别诊断有临床价值。所有检测指标中CRP的特异度、阳性预测值、阴性预测值、约登指数最高。" @default.
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- W617456472 date "2011-01-01" @default.
- W617456472 modified "2023-09-27" @default.
- W617456472 title "触珠蛋白、α1-酸性糖蛋白和C反应蛋白对细菌性及病毒性感染患儿的鉴别诊断价值" @default.
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