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• W61783654 abstract "Back to table of contents Previous article Next article No AccessRelationship of childhood anxiety to adult panic disorder: correlates and influence on coursePublished Online:1 Apr 2006https://doi.org/10.1176/ajp.153.3.376AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractOBJECTIVE: This study investigated the correlates of a childhood history of anxiety disorders in adult patients participating in a longitudinal study of panic disorder. The authors hypothesized that a history of anxiety during childhood would be associated with higher rates of comorbid anxiety and depressive disorders, greater likelihood of anxiety disorders in family members, and greater chronicity, as reflected by decreased time spent in remission. METHOD: The presence of a childhood history of anxiety disorders was assessed by structured interview, and its association with comorbid anxiety and depressive disorders, family history, and select anxiety severity variables was examined in a replication sample of 94 patients. The influence of childhood anxiety on the prospectively ascertained course of disorder was assessed in a full group of 194 patients. RESULTS: Over half (54%) of the patients experienced anxiety disorders during childhood. These patients experienced higher rates of comorbid anxiety and depression, family history of anxiety, and increased levels of agoraphobia, panic frequency, and global severity of illness at baseline evaluation. Childhood anxiety disorders were not independently associated with the number of months in remission or the severity of illness over time, although a modest effect for this variable was evident when degree of avoidance and anxiety sensitivity at baseline were statistically controlled. CONCLUSIONS: Adult panic patients with a history of anxiety disorders in childhood have elevated rates of comorbid anxiety and depressive disorders and a tendency toward increased avoidance, but there was not strong evidence that these patients respond differently to treatment over time. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. 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FiguresReferencesCited byDetailsCited byFamily Conflicts, Anxiety and Depressive Symptoms, and Suicidal Ideation of Chinese Adolescents in Hong Kong8 February 2021 | Applied Research in Quality of Life, Vol. 16, No. 6ANALISANDO OS DISTURBIOS FUNCIONAIS DO TRANSTORNO DE ANSIEDADE EM ADOLESCENTES DE 14 A 19 ANOS PELA TERAPIA OCUPACIONAL14 September 2021 | RECISATEC - REVISTA CIENTÍFICA SAÚDE E TECNOLOGIA - ISSN 2763-8405, Vol. 1, No. 2Shyness and anxiety: Protective role of extraversionPersonality and Individual Differences, Vol. 178Development-Dependent Plasticity in Vasoactive Intestinal Polypeptide Neurons in the Infralimbic Cortex4 February 2021 | Cerebral Cortex Communications, Vol. 2, No. 1lifetime exposure to traffic-related air pollution and symptoms of depression and anxiety at age 12 yearsEnvironmental Research, Vol. 173Synapse, Vol. 73, No. 6Biological Psychiatry, Vol. 86, No. 9Effect of Early-Life Fluoxetine on Anxiety-Like Behaviors in BDNF Val66Met MiceIva Dincheva, Ph.D., Jianmin Yang, Ph.D., Anfei Li, B.S., Tina Marinic, B.A., Helena Freilingsdorf, M.D., Chienchun Huang, B.S., B.J. 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Hirshfeld-Becker, Ph.D., Jerrold F. Rosenbaum, M.D., Christine Hérot, Ed.D., Deborah Friedman, B.A., Nancy Snidman, Ph.D., Jerome Kagan, Ph.D., and Stephen V. Faraone, Ph.D.1 October 2001 | American Journal of Psychiatry, Vol. 158, No. 10Gender-related differences in the onset of panic disorder9 October 2008 | Acta Psychiatrica Scandinavica, Vol. 103, No. 3American Journal of Medical Genetics, Vol. 105, No. 2Depression and Anxiety, Vol. 14, No. 4Revista Brasileira de Psiquiatria, Vol. 23, No. 3Journal of the American Veterinary Medical Association, Vol. 219, No. 4A Controlled Study of Behavioral Inhibition in Children of Parents With Panic Disorder and DepressionJerrold F. Rosenbaum, M.D., Joseph Biederman, M.D., Dina R. Hirshfeld-Becker, Ph.D., Jerome Kagan, Ph.D., Nancy Snidman, Ph.D., Deborah Friedman, B.A., Allan Nineberg, M.D., Daniel J. Gallery, Psy.D., and Stephen V. Faraone, Ph.D.1 December 2000 | American Journal of Psychiatry, Vol. 157, No. 12Yohimbine Challenge in Children With Anxiety DisordersFloyd R. Sallee, M.D., Ph.D., Gopalan Sethuraman, Ph.D., Lauren Sine, M.S., and Hong Liu, M.D.1 August 2000 | American Journal of Psychiatry, Vol. 157, No. 8History of childhood attention deficit hyperactivity disorder (ADHD) features among adults with panic disorderJournal of Affective Disorders, Vol. 58, No. 2Panic: Course, Complications and Treatment of Panic Disorder4 December 2016 | Journal of Psychopharmacology, Vol. 14, No. 2_suppl1Human Psychopharmacology: Clinical and Experimental, Vol. 15, No. 8Clinical Psychology Review, Vol. 20, No. 4Journal of Anxiety Disorders, Vol. 14, No. 3Child and Adolescent Psychiatric Clinics of North America, Vol. 9, No. 1Revista Brasileira de Psiquiatria, Vol. 22, No. suppl 2Pathophysiology of childhood anxiety disordersBiological Psychiatry, Vol. 46, No. 11Pediatric Clinics of North America, Vol. 46, No. 5Journal of Child and Adolescent Psychopharmacology, Vol. 9, No. 1Panic and Phobic Anxiety: Defining Phenotypes for Genetic StudiesJordan W. Smoller, M.D., M.Sc., and Ming T. Tsuang, M.D., Ph.D., D.Sc.1 September 1998 | American Journal of Psychiatry, Vol. 155, No. 9Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 37, No. 6ANXIETY AND DEPRESSION IN ADVANCED LUNG DISEASEClinics in Chest Medicine, Vol. 18, No. 3Journal of the American Academy of Child & Adolescent Psychiatry, Vol. 35, No. 9 Volume 153Issue 3 March 1996Pages 376-381 Metrics PDF download History Published online 1 April 2006 Published in print 1 March 1996" @default.
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