Matches in SemOpenAlex for { <https://semopenalex.org/work/W6190487> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W6190487 endingPage "8" @default.
- W6190487 startingPage "122" @default.
- W6190487 abstract "Proteus mirabilis is an important pathogen isolated from both community-acquired and health-care associated infections. Acquired AmpC-type beta-lactamases represent an important mechanism of resistance to extended-spectrum cephalosporins and are emerging in several European countries. The objective of this work was to know the prevalence of acquired AmpC beta-lactamase producing P. mirabilis over the last three years and eight months and their clonal relationships comparing MALDI-TOF and automated rep-PCR results.P. mirabilis isolates (n= 1,396) were obtained from routine cultures at the University Hospital Complex of Santiago de Compostela from January 2006 to August 2009. Identification to the species level and antimicrobial susceptibility testing were achieved with Vitek 2. The isolates showing intermediate or total resistance to amoxicillin-clavulanic and cefoxitin, cefotaxime or ceftazidime were selected for AmpC phenotypic detection by double-disk synergy test, and molecular confirmation by multiplex PCR. Molecular typing of the isolates was performed by automated rep-PCR and MALDI-TOF.For the last three years and eight months, the prevalence of AmpC-producing P. mirabilis increased from 0.17% to 4.5%, mainly associated with urinary tract infection in elderly outpatients. In all cases, plasmidic AmpC belonging to LAT/CMY lineage were detected. A high genetic variability was seen with both, rep-PCR and MALDI-TOF MS.AmpC-producing P. mirabilis is an emergent pathogen. The high genetic variability detected suggests that the spread of the resistance mechanism is more probable than a clone dispersion. Automated rep-PCR and MALDI-TOF MS show as fast and decisive methods for bacterial strain typing in clinical microbiology laboratories." @default.
- W6190487 created "2016-06-24" @default.
- W6190487 creator A5002411048 @default.
- W6190487 creator A5016998418 @default.
- W6190487 creator A5031074803 @default.
- W6190487 creator A5050136716 @default.
- W6190487 creator A5052231803 @default.
- W6190487 creator A5070196867 @default.
- W6190487 date "2012-06-01" @default.
- W6190487 modified "2023-09-27" @default.
- W6190487 title "[Plasmid-mediated AMPc producing Proteus mirabilis in the Health Care Area of Santiago de Compostela: molecular and epidemiological analysis by rep-PCR and MALDI-TOF]." @default.
- W6190487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22707100" @default.
- W6190487 hasPublicationYear "2012" @default.
- W6190487 type Work @default.
- W6190487 sameAs 6190487 @default.
- W6190487 citedByCount "0" @default.
- W6190487 crossrefType "journal-article" @default.
- W6190487 hasAuthorship W6190487A5002411048 @default.
- W6190487 hasAuthorship W6190487A5016998418 @default.
- W6190487 hasAuthorship W6190487A5031074803 @default.
- W6190487 hasAuthorship W6190487A5050136716 @default.
- W6190487 hasAuthorship W6190487A5052231803 @default.
- W6190487 hasAuthorship W6190487A5070196867 @default.
- W6190487 hasConcept C104317684 @default.
- W6190487 hasConcept C135763542 @default.
- W6190487 hasConcept C2776124114 @default.
- W6190487 hasConcept C2776460866 @default.
- W6190487 hasConcept C2776968632 @default.
- W6190487 hasConcept C2777050379 @default.
- W6190487 hasConcept C2777637488 @default.
- W6190487 hasConcept C2778039505 @default.
- W6190487 hasConcept C2778719061 @default.
- W6190487 hasConcept C2779489039 @default.
- W6190487 hasConcept C2779631663 @default.
- W6190487 hasConcept C49105822 @default.
- W6190487 hasConcept C501593827 @default.
- W6190487 hasConcept C523546767 @default.
- W6190487 hasConcept C54355233 @default.
- W6190487 hasConcept C64778159 @default.
- W6190487 hasConcept C86803240 @default.
- W6190487 hasConcept C89423630 @default.
- W6190487 hasConcept C90583042 @default.
- W6190487 hasConcept C94665300 @default.
- W6190487 hasConcept C97669555 @default.
- W6190487 hasConceptScore W6190487C104317684 @default.
- W6190487 hasConceptScore W6190487C135763542 @default.
- W6190487 hasConceptScore W6190487C2776124114 @default.
- W6190487 hasConceptScore W6190487C2776460866 @default.
- W6190487 hasConceptScore W6190487C2776968632 @default.
- W6190487 hasConceptScore W6190487C2777050379 @default.
- W6190487 hasConceptScore W6190487C2777637488 @default.
- W6190487 hasConceptScore W6190487C2778039505 @default.
- W6190487 hasConceptScore W6190487C2778719061 @default.
- W6190487 hasConceptScore W6190487C2779489039 @default.
- W6190487 hasConceptScore W6190487C2779631663 @default.
- W6190487 hasConceptScore W6190487C49105822 @default.
- W6190487 hasConceptScore W6190487C501593827 @default.
- W6190487 hasConceptScore W6190487C523546767 @default.
- W6190487 hasConceptScore W6190487C54355233 @default.
- W6190487 hasConceptScore W6190487C64778159 @default.
- W6190487 hasConceptScore W6190487C86803240 @default.
- W6190487 hasConceptScore W6190487C89423630 @default.
- W6190487 hasConceptScore W6190487C90583042 @default.
- W6190487 hasConceptScore W6190487C94665300 @default.
- W6190487 hasConceptScore W6190487C97669555 @default.
- W6190487 hasIssue "2" @default.
- W6190487 hasLocation W61904871 @default.
- W6190487 hasOpenAccess W6190487 @default.
- W6190487 hasPrimaryLocation W61904871 @default.
- W6190487 hasRelatedWork W2051278910 @default.
- W6190487 hasRelatedWork W2075795596 @default.
- W6190487 hasRelatedWork W2132180316 @default.
- W6190487 hasRelatedWork W2145975094 @default.
- W6190487 hasRelatedWork W2347283549 @default.
- W6190487 hasRelatedWork W2468898955 @default.
- W6190487 hasRelatedWork W2772629729 @default.
- W6190487 hasRelatedWork W2782798893 @default.
- W6190487 hasRelatedWork W6190487 @default.
- W6190487 hasRelatedWork W2779560114 @default.
- W6190487 hasVolume "25" @default.
- W6190487 isParatext "false" @default.
- W6190487 isRetracted "false" @default.
- W6190487 magId "6190487" @default.
- W6190487 workType "article" @default.