Matches in SemOpenAlex for { <https://semopenalex.org/work/W61978206> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W61978206 endingPage "F812" @default.
- W61978206 startingPage "F806" @default.
- W61978206 abstract "Radiation inactivation was used to determine the nature and molecular weight of water and urea transport pathways in brush border membrane vesicles (BBMV) isolated from rabbit renal cortex. BBMV were frozen to -50 degrees C, irradiated with 1.5 MeV electrons, thawed, and assayed for transport or enzyme activity. The freezing process had no effect on enzyme or transport kinetics. BBMV alkaline phosphatase activity gave linear ln(activity) vs. radiation dose plots with a target size of 68 +/- 3 kDa, similar to previously reported values. Water and solute transport were measured using the stopped-flow light-scattering technique. The rates of acetamide and osmotic water transport did not depend on radiation dose (0-7 Mrad), suggesting that transport of these substances does not require a protein carrier. In contrast, urea and thiourea transport gave linear ln(activity) vs. dose curves with a target size of 125-150 kDa; 400 mM urea inhibited thiourea flux by -50% at 0 and 4.7 Mrad, showing that radiation does not affect inhibitor binding to surviving transporters. These studies suggest that BBMV urea transport requires a membrane protein, whereas osmotic water transport does not." @default.
- W61978206 created "2016-06-24" @default.
- W61978206 creator A5000298503 @default.
- W61978206 creator A5069189718 @default.
- W61978206 creator A5072978671 @default.
- W61978206 creator A5077746353 @default.
- W61978206 creator A5080702113 @default.
- W61978206 creator A5089625707 @default.
- W61978206 date "1985-12-01" @default.
- W61978206 modified "2023-09-26" @default.
- W61978206 title "Radiation inactivation studies of renal brush border water and urea transport" @default.
- W61978206 doi "https://doi.org/10.1152/ajprenal.1985.249.6.f806" @default.
- W61978206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3934983" @default.
- W61978206 hasPublicationYear "1985" @default.
- W61978206 type Work @default.
- W61978206 sameAs 61978206 @default.
- W61978206 citedByCount "6" @default.
- W61978206 crossrefType "journal-article" @default.
- W61978206 hasAuthorship W61978206A5000298503 @default.
- W61978206 hasAuthorship W61978206A5069189718 @default.
- W61978206 hasAuthorship W61978206A5072978671 @default.
- W61978206 hasAuthorship W61978206A5077746353 @default.
- W61978206 hasAuthorship W61978206A5080702113 @default.
- W61978206 hasAuthorship W61978206A5089625707 @default.
- W61978206 hasConcept C12554922 @default.
- W61978206 hasConcept C127413603 @default.
- W61978206 hasConcept C130316041 @default.
- W61978206 hasConcept C185592680 @default.
- W61978206 hasConcept C24840226 @default.
- W61978206 hasConcept C2778423325 @default.
- W61978206 hasConcept C2780365088 @default.
- W61978206 hasConcept C2988574769 @default.
- W61978206 hasConcept C2992163139 @default.
- W61978206 hasConcept C41625074 @default.
- W61978206 hasConcept C5426402 @default.
- W61978206 hasConcept C55493867 @default.
- W61978206 hasConcept C57581600 @default.
- W61978206 hasConcept C57947595 @default.
- W61978206 hasConcept C86803240 @default.
- W61978206 hasConcept C87717796 @default.
- W61978206 hasConcept C99975950 @default.
- W61978206 hasConceptScore W61978206C12554922 @default.
- W61978206 hasConceptScore W61978206C127413603 @default.
- W61978206 hasConceptScore W61978206C130316041 @default.
- W61978206 hasConceptScore W61978206C185592680 @default.
- W61978206 hasConceptScore W61978206C24840226 @default.
- W61978206 hasConceptScore W61978206C2778423325 @default.
- W61978206 hasConceptScore W61978206C2780365088 @default.
- W61978206 hasConceptScore W61978206C2988574769 @default.
- W61978206 hasConceptScore W61978206C2992163139 @default.
- W61978206 hasConceptScore W61978206C41625074 @default.
- W61978206 hasConceptScore W61978206C5426402 @default.
- W61978206 hasConceptScore W61978206C55493867 @default.
- W61978206 hasConceptScore W61978206C57581600 @default.
- W61978206 hasConceptScore W61978206C57947595 @default.
- W61978206 hasConceptScore W61978206C86803240 @default.
- W61978206 hasConceptScore W61978206C87717796 @default.
- W61978206 hasConceptScore W61978206C99975950 @default.
- W61978206 hasIssue "6" @default.
- W61978206 hasLocation W619782061 @default.
- W61978206 hasLocation W619782062 @default.
- W61978206 hasOpenAccess W61978206 @default.
- W61978206 hasPrimaryLocation W619782061 @default.
- W61978206 hasRelatedWork W1520706903 @default.
- W61978206 hasRelatedWork W1962321112 @default.
- W61978206 hasRelatedWork W1970977774 @default.
- W61978206 hasRelatedWork W2007776115 @default.
- W61978206 hasRelatedWork W2013621780 @default.
- W61978206 hasRelatedWork W2013878656 @default.
- W61978206 hasRelatedWork W2032446409 @default.
- W61978206 hasRelatedWork W2239327948 @default.
- W61978206 hasRelatedWork W2329889215 @default.
- W61978206 hasRelatedWork W61978206 @default.
- W61978206 hasVolume "249" @default.
- W61978206 isParatext "false" @default.
- W61978206 isRetracted "false" @default.
- W61978206 magId "61978206" @default.
- W61978206 workType "article" @default.