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- W620140894 abstract "Valproate is an anticonvulsant drug which is approved for use in epilepsy and bipolar disorder. Gastrointestinal adverse effects are common, particularly at the start of therapy. Important adverse effects include pancreatitis, hepatitis, weight gain and sedation. There is an increased risk of fetal abnormalities if valproate is taken in pregnancy. Measuring concentrations of serum valproate is often unnecessary. They do not correlate closely with its therapeutic effects. If withdrawal of valproate is required, this should be done slowly if possible. Rapid cessation may provoke seizures in patients with epilepsy." @default.
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- W620140894 date "2014-08-01" @default.
- W620140894 modified "2023-10-13" @default.
- W620140894 title "Safe use of sodium valproate" @default.
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- W620140894 doi "https://doi.org/10.18773/austprescr.2014.048" @default.
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