Matches in SemOpenAlex for { <https://semopenalex.org/work/W620714503> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W620714503 abstract "Pregnancy involves interactions of numerous growth factors, proteins and hormones exerting their biological functions in cellular growth, migration, differentiation and signal transduction. FGF2, STAT5A and UTMP are important mediators of intra-cellular signals transduction and transcription functions during pregnancy. Mutations in these genes will eventually disrupt their biological functions leading to embryonic death. The present study was designed to analyze in silico the SNPs in buffalo FGF2, STAT5A and UTMP genes by homology modeling. In the present study genomic DNA was isolated from the blood of 75 adult female buffaloes which was subsequently used for the amplification of FGF2, STAT5A and UTMP gene specific regions. PCR products of 167 bp, 429 bp and 279 bp were obtained for specific FGF2, STAT5A and UTMP gene regions, respectively. Sequenced PCR products showed 96–97% similarity with bovine sequences on BLAST analysis for all the 3 gene segments. Sequence analysis showed 9, 3 and 9 distinct nucleotide differences in the regions of FGF2, STAT5A, UTMP genes, respectively. Furthermore, based on the nucleotide difference 3 variants for FGF2 and UTMP genes were deduced in comparison with the bovine sequence. Promotor region analysis of FGF2 and homology modeling of STAT5A and UTMP gene revealed modification in the protein structure arising due to the presence of nucleotide changes. In the present study single nucleotide polymorphism were deduced in FGF2, STAT5A and UTMP gene region of buffalo and homology modeling of the studied gene portions were carried out." @default.
- W620714503 created "2016-06-24" @default.
- W620714503 creator A5012641286 @default.
- W620714503 creator A5044558554 @default.
- W620714503 creator A5068989615 @default.
- W620714503 date "2015-06-10" @default.
- W620714503 modified "2023-09-30" @default.
- W620714503 title "Homology modeling of single nuleotide polymorphisms in candidate genes controlling embryonic growth of buffalo" @default.
- W620714503 cites W1984064440 @default.
- W620714503 cites W1984747547 @default.
- W620714503 cites W1989841936 @default.
- W620714503 cites W2009763493 @default.
- W620714503 cites W2013893889 @default.
- W620714503 cites W2019753523 @default.
- W620714503 cites W2039421923 @default.
- W620714503 cites W2046966307 @default.
- W620714503 cites W2060259273 @default.
- W620714503 cites W2073187113 @default.
- W620714503 cites W2074421098 @default.
- W620714503 cites W2075793022 @default.
- W620714503 cites W2096150082 @default.
- W620714503 cites W2099886875 @default.
- W620714503 cites W2106024556 @default.
- W620714503 cites W2108654230 @default.
- W620714503 cites W2151625863 @default.
- W620714503 cites W2160548275 @default.
- W620714503 cites W2165348927 @default.
- W620714503 cites W2171023616 @default.
- W620714503 doi "https://doi.org/10.56093/ijans.v85i6.49289" @default.
- W620714503 hasPublicationYear "2015" @default.
- W620714503 type Work @default.
- W620714503 sameAs 620714503 @default.
- W620714503 citedByCount "0" @default.
- W620714503 crossrefType "journal-article" @default.
- W620714503 hasAuthorship W620714503A5012641286 @default.
- W620714503 hasAuthorship W620714503A5044558554 @default.
- W620714503 hasAuthorship W620714503A5068989615 @default.
- W620714503 hasBestOaLocation W6207145031 @default.
- W620714503 hasConcept C104317684 @default.
- W620714503 hasConcept C135763542 @default.
- W620714503 hasConcept C153209595 @default.
- W620714503 hasConcept C165525559 @default.
- W620714503 hasConcept C2775905019 @default.
- W620714503 hasConcept C54355233 @default.
- W620714503 hasConcept C61053724 @default.
- W620714503 hasConcept C86803240 @default.
- W620714503 hasConceptScore W620714503C104317684 @default.
- W620714503 hasConceptScore W620714503C135763542 @default.
- W620714503 hasConceptScore W620714503C153209595 @default.
- W620714503 hasConceptScore W620714503C165525559 @default.
- W620714503 hasConceptScore W620714503C2775905019 @default.
- W620714503 hasConceptScore W620714503C54355233 @default.
- W620714503 hasConceptScore W620714503C61053724 @default.
- W620714503 hasConceptScore W620714503C86803240 @default.
- W620714503 hasIssue "6" @default.
- W620714503 hasLocation W6207145031 @default.
- W620714503 hasOpenAccess W620714503 @default.
- W620714503 hasPrimaryLocation W6207145031 @default.
- W620714503 hasRelatedWork W2029633625 @default.
- W620714503 hasRelatedWork W2034625591 @default.
- W620714503 hasRelatedWork W2040571417 @default.
- W620714503 hasRelatedWork W2045313050 @default.
- W620714503 hasRelatedWork W2050573380 @default.
- W620714503 hasRelatedWork W2069153243 @default.
- W620714503 hasRelatedWork W2074557265 @default.
- W620714503 hasRelatedWork W2076127294 @default.
- W620714503 hasRelatedWork W2389486678 @default.
- W620714503 hasRelatedWork W332976159 @default.
- W620714503 hasVolume "85" @default.
- W620714503 isParatext "false" @default.
- W620714503 isRetracted "false" @default.
- W620714503 magId "620714503" @default.
- W620714503 workType "article" @default.