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- W620811 abstract "Abstract: We have studied the organization of DNA within the nucleosome, the subunit of chromatin structure. The DNA within the nucleosome core is susceptible to attack by a variety of nucleases; the points of attack are restricted to sites that are separated by intervals of ten nucleotides on each strand. We compare the modes of action of three different nucleases. In each case, the enzyme has a characteristic cutting pattern in which cuts on opposite strands are offset, or staggered, relative to one another. Although the cutting sites are different for each enzyme, the centers of symmetry of their cuts all coincide. This suggests that there is a common periodic recognition site on the nucleosome for all of the enzymes." @default.
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- W620811 date "1978-01-01" @default.
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- W620811 title "DNA FOLDING AND HISTONE ORGANIZATION IN CHROMATIN" @default.
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- W620811 doi "https://doi.org/10.1016/b978-0-12-045450-1.50018-4" @default.
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