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- W62197846 abstract "The circadian variation in platelet function may play a role in the morning increase of coronary thrombotic complications. The circadian variation of plasma beta-thromboglobulin levels--as an indicator of in vivo platelet activation--was investigated in seven healthy volunteers using a commercial radioimmunoassay kit. There was a statistically significant rhythm culminating with an amplitude of 30 micrograms/l (95% tolerance interval/15-45 micrograms/l) at 10.00 hours (95% tolerance interval/07.00-13.00 hours). The morning increase of plasma beta-thromboglobulin indicates an increased in vivo platelet activation at this time of day. This finding could correlate with the morning peak in the onset of myocardial infarction. It might also help in timing therapy of diseases which are associated with platelet hyperactivation." @default.
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- W62197846 date "1992-02-01" @default.
- W62197846 modified "2023-09-27" @default.
- W62197846 title "Circadian rhythm of plasma beta-thromboglobulin in healthy human subjects" @default.
- W62197846 doi "https://doi.org/10.1097/00001721-199202000-00015" @default.
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