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- W62399415 endingPage "91" @default.
- W62399415 startingPage "73" @default.
- W62399415 abstract "Although conventional vaccines have been demonstrated to be highly effective in stimulating protective immunity against a wide range of microorganisms, there are still instances in which suitable vaccines are lacking. For example, the inability to culture large quantities of numerous protozoal pathogens in vitro has prevented the development of conventional vaccines for these organisms. Other obstacles to the development of conventional vaccines include the poor humoral response of infants under the age of 2 years to certain polysaccharide antigens present on encapsulated bacteria (i.e., Neisseria meningitidis, Vibrio cholera, and Hemophilus influenzae) (1, 2). Also, the recent spread of the human immunodeficiency virus type 1 (HIV-1) and its possible origin and evolution from viruses isolated from nonhuman primate species has pointed up the necessity of developing a vaccine that is incapable of reverting to a virulent form. These obstacles have led to the development of a new generation of vaccines. Recombinant proteins, synthetic peptides, and anti-idiotypic antibodies represent relatively new technologies that are currently being examined for their potential use in stimulating immunity against various microorganisms (reviewed in 3 and 4). This report will review studies from this laboratory that examine the potential use of anti-Idiotype to generate immunity to HIV-1 and hepatitis B virus (HBV)." @default.
- W62399415 created "2016-06-24" @default.
- W62399415 creator A5068076273 @default.
- W62399415 creator A5086162707 @default.
- W62399415 date "1991-01-01" @default.
- W62399415 modified "2023-10-16" @default.
- W62399415 title "Anti-Idiotypic Antibodies as Potential Viral Vaccines" @default.
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