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- W62486002 abstract "Abstract Several chlorinated hydrocarbon pesticides, considered to be specific acaricides, were shown to be in vitro inhibitors of the ATPase enzyme system from blue gill fish brain homogenates. Mitochondrial (oligomycin-sensitive) Mg2+ATPase from fish brain was inhibited by each chlorinated bridged biphenyl compound (ovex, chlorberside, chlorobenzilate, 4,4′-dichloro-a-methylbenzhydrol, and 2,4-dichlorophenyl benzenesulfonate). Moreover, these compounds were relatively ineffective on Na+-K+ATPase and the oligomycin-insensitive Mg2+ATPase. In contrast, decachlorobi-2, 4-cyclopentadien-1-yl, a bicyclic pentadienyl compound, inhibited Na+-K+ATPase and oligomycin-insensitive Mg2+ATPase. An alkyl aryl sulfite, 2-(p-tert-butyl-phenoxy)-1-methylethyl 2-chloroethyl sulfite, was relatively ineffective on the ATPase enzyme system. An in vivo correlation, based upon behavior of mites, was shown between the effect on the ATPase system and acaricidal activity." @default.
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- W62486002 date "1972-12-01" @default.
- W62486002 modified "2023-09-26" @default.
- W62486002 title "The sensitivity of fish brain atpases to ogranochlorine acaricides" @default.
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- W62486002 doi "https://doi.org/10.1016/0024-3205(72)90267-6" @default.
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