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- W62519273 abstract "The effect of fructose on glycogen synthesis was examined in the perfused liver of starved rats. With increasing fructose concentration in the perfusate, glycogen synthesis and the % a form of glycogen synthase increased to a maximum at 2 mM and then decreased, progressively. The glucose 6-P level increased with the increase in fructose concentration. On the other hand, the ATP content was unchanged at a concentration of 2 mM or less and decreased at 3 mM or more. We also showed that the stimulation of glycogen synthesis by fructose at a concentration of 2 mM or less was due to activation of glycogen synthase by accumulated glucose 6-P and that ATP depletion at a concentration of 3 mM or more caused an increase in phosphorylase a and a decrease in glycogen synthase activity even in the presence of a high concentration of glucose 6-P." @default.
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- W62519273 date "1990-01-01" @default.
- W62519273 modified "2023-09-23" @default.
- W62519273 title "Effect of fructose on glycogen synthesis in the perfused rat liver." @default.
- W62519273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2107805" @default.
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