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- W6263135 abstract "Over the past twenty years, 630 total thyroidectomies have been performed: 121 (101 females, 20 males) for Grave's disease; 113 (81 females, 32 males) for cold thyroid nodules and head, neck, and thorax irradiation during childhood; and 396 (317 females, 70 males) for a cold dominant nodule of the thyroid. One hundred eighty-three patients had papillary follicular carcinoma, four had medullary carcinoma, five had anaplastic or small cell carcinoma, and one had reticulum cell sarcoma. In this series, patients with Grave's disease had a 5 per cent malignancy rate. Those who had had radiation to the head and neck and thorax during childhood had a 42.5 per cent malignancy rate, and those with a cold dominant thyroid nodule had a 35 per cent malignancy rate. A comparison of the complications and sequelae of total thyroidectomy to those of subtotal thyroidectomy revealed that they were essentially the same. However, the multifold risk of complications in a second neck exploration, plus the anesthetic risk and the time delay when further surgery was then needed after a subtotal procedure, are completely avoided by performing total thyroidectomy primarily. Thus, when surgery is indicated for the management of Grave's disease, thyroid nodules and childhood irradiation, and cold dominant nodules of the thyroid suspected of carcinoma, it is our contention and recommendation that total thyroidectomy be performed." @default.
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- W6263135 date "1978-10-01" @default.
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- W6263135 title "Total thyroidectomy" @default.
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- W6263135 doi "https://doi.org/10.1016/0002-9610(78)90259-3" @default.
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