Matches in SemOpenAlex for { <https://semopenalex.org/work/W626326533> ?p ?o ?g. }
- W626326533 abstract "Visual working memory, a limited temporary storage system for relevant information, isa critical contributor to many essential cognitive functions. In this thesis, I aimed toinvestigate some of the mechanisms underlying working memory in healthy humans andneurological patients, as well as its modulation by processes attributed to attention andthe neurotransmitter dopamine.There currently is an important controversy regarding models of working memory. Iinvestigated whether a resource model of memory (which argues for a limited resourcedistributed amongst to-be-remembered items) might be extended to the domain of visualmotion. The results suggest that this is indeed be the case, supporting the utility of thismodel as a general conceptual framework for understanding working memory across arange of visual features and modes of presentation (Chapter 2).A comprehensive model of working memory should consider its relationship withattention. My findings point to an intimate yet highly specific relationship between thesetwo processes, demonstrating that attention is essential for maintenance of integratedfeatures within working memory (Chapters 2 and 4). Further, evidence for a causal roleof early visual areas in maintenance of items in focus of attention, compared to the fullcontent of working memory, is provided using transcranial magnetic stimulation(Chapter 3).Finally, I investigated neuromodulation of working memory processes by dopamine inpatients with dopamine dysfunction (Parkinson’s disease) and using the dopamineagonist, Cabergoline, in healthy controls. The results demonstrate that dopamine canmodulate working memory precision (Chapter 5 and 6). Furthermore, deficits inworking memory were also observed in individuals with glucocerebrosidase mutationswho have a significantly raised risk of developing Parkinson’s disease (Chapter 7). Idiscuss the possibility that specific deficits in working memory might provide acognitive marker of risk for neurodegeneration and development of Parkinson’s disease." @default.
- W626326533 created "2016-06-24" @default.
- W626326533 creator A5008869618 @default.
- W626326533 date "2013-07-28" @default.
- W626326533 modified "2023-09-23" @default.
- W626326533 title "Modulation of working memory" @default.
- W626326533 cites W1572495684 @default.
- W626326533 cites W1584047372 @default.
- W626326533 cites W1589353809 @default.
- W626326533 cites W1676198469 @default.
- W626326533 cites W1747565446 @default.
- W626326533 cites W1759162153 @default.
- W626326533 cites W1805361895 @default.
- W626326533 cites W1847168837 @default.
- W626326533 cites W1901661521 @default.
- W626326533 cites W1934525866 @default.
- W626326533 cites W1934970405 @default.
- W626326533 cites W1963801412 @default.
- W626326533 cites W1963971262 @default.
- W626326533 cites W1964320082 @default.
- W626326533 cites W1968119089 @default.
- W626326533 cites W1968504063 @default.
- W626326533 cites W1968758382 @default.
- W626326533 cites W1969635251 @default.
- W626326533 cites W1969880629 @default.
- W626326533 cites W1970035031 @default.
- W626326533 cites W1970573088 @default.
- W626326533 cites W1971309447 @default.
- W626326533 cites W1971762790 @default.
- W626326533 cites W1972927034 @default.
- W626326533 cites W1974898145 @default.
- W626326533 cites W1975400414 @default.
- W626326533 cites W1975749383 @default.
- W626326533 cites W1976232810 @default.
- W626326533 cites W1980696279 @default.
- W626326533 cites W1980732041 @default.
- W626326533 cites W1980871601 @default.
- W626326533 cites W1981499926 @default.
- W626326533 cites W1982197468 @default.
- W626326533 cites W1982224533 @default.
- W626326533 cites W1984314602 @default.
- W626326533 cites W1984925818 @default.
- W626326533 cites W1986951455 @default.
- W626326533 cites W1987093823 @default.
- W626326533 cites W1987769172 @default.
- W626326533 cites W1988986349 @default.
- W626326533 cites W1989490147 @default.
- W626326533 cites W1992049705 @default.
- W626326533 cites W1992253341 @default.
- W626326533 cites W1992337477 @default.
- W626326533 cites W1992936460 @default.
- W626326533 cites W1993958047 @default.
- W626326533 cites W1994357188 @default.
- W626326533 cites W1995316098 @default.
- W626326533 cites W1995412600 @default.
- W626326533 cites W1995778321 @default.
- W626326533 cites W1995868850 @default.
- W626326533 cites W1996001145 @default.
- W626326533 cites W1997230335 @default.
- W626326533 cites W1999076139 @default.
- W626326533 cites W1999110283 @default.
- W626326533 cites W1999479596 @default.
- W626326533 cites W2000217686 @default.
- W626326533 cites W2002715641 @default.
- W626326533 cites W2003119385 @default.
- W626326533 cites W2003471045 @default.
- W626326533 cites W2003812482 @default.
- W626326533 cites W2004150192 @default.
- W626326533 cites W2006025735 @default.
- W626326533 cites W2007131990 @default.
- W626326533 cites W2008275505 @default.
- W626326533 cites W2008433387 @default.
- W626326533 cites W2011243006 @default.
- W626326533 cites W2013142139 @default.
- W626326533 cites W2013320439 @default.
- W626326533 cites W2013449353 @default.
- W626326533 cites W2014089188 @default.
- W626326533 cites W2014347572 @default.
- W626326533 cites W2016120610 @default.
- W626326533 cites W2019210871 @default.
- W626326533 cites W2021001546 @default.
- W626326533 cites W2021742211 @default.
- W626326533 cites W2022961682 @default.
- W626326533 cites W2023416109 @default.
- W626326533 cites W2023584795 @default.
- W626326533 cites W2023889744 @default.
- W626326533 cites W2025054170 @default.
- W626326533 cites W2025164243 @default.
- W626326533 cites W2025264833 @default.
- W626326533 cites W2025374131 @default.
- W626326533 cites W2026235827 @default.
- W626326533 cites W2026451952 @default.
- W626326533 cites W2027377112 @default.
- W626326533 cites W2028072328 @default.
- W626326533 cites W2029806415 @default.
- W626326533 cites W2030187260 @default.
- W626326533 cites W2030364234 @default.
- W626326533 cites W2031020345 @default.
- W626326533 cites W2031365272 @default.
- W626326533 cites W2031534534 @default.