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- W62697226 abstract "Many difficulties associated with immuno(metric) assay kits designed for quantification of a particular biomarker arise from their variation in specificity and binding affinity of the employed antibodies. Other important sources causing varying assay results are the use of different standard preparations in these kits and the nonuniform preanalytical specimen processing procedures employed, each of which should be subjected to standardization. To improve the performance and comparability of assays, continuous interlaboratory external quality control procedures are needed. Such quality assurance programs provide a forum for expert laboratory investigators to discuss technical details and to exchange laboratory issues and related practical information. This chapter addresses some of these issues and presents initial analytical validation procedures of newly developed biomarker assays, the validation of already established assay procedures for routine use on a day-to-day basis, and finally discusses some aspects on adequate (external) quality control proficiency testing." @default.
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- W62697226 date "2006-01-01" @default.
- W62697226 modified "2023-09-23" @default.
- W62697226 title "Analytical Aspects of Biomarker Immunoassays in Cancer Research" @default.
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- W62697226 doi "https://doi.org/10.1385/1-59259-915-x:017" @default.
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