Matches in SemOpenAlex for { <https://semopenalex.org/work/W62698972> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W62698972 endingPage "100" @default.
- W62698972 startingPage "1096" @default.
- W62698972 abstract "Atopic dermatitis is a chronic inflammatory skin disease with a relapsing course. Topical corticosteroids are the usual treatment of atopic dermatitis. Long-term use of topical corticosteroids may lead to local side effects, such as skin atrophy, and systemic side effects, such as induction of hypothalamus-pituitary-adrenal axis suppression. Tacrolimus and pimecrolimus are new topical immunosuppressive drugs known as topical immunomodulators (TIMs). Clinical efficacy of these drugs has been demonstrated in various long- and short-term placebo-controlled studies. The efficacy oftacrolimus is comparable to a class 2 dermatocorticosteroid and the efficacy of pimecrolimus is comparable to a class 1 dermatocorticosteroid. A major advantage of the use of TIMs is that they do not result in skin atrophy. Tacrolimus may cause local irritation, which mostly disappears after 2 weeks. Little is known about the long-term safety of TIMs. It is expected that TIMs will have an important role in the treatment of mild to moderate atopic dermatitis. Combined treatment with dermatocorticosteroids and TIMs needs further investigation. For patients with severe atopic dermatitis, the addition of TIMs to oral immunosuppressive drugs, such as cyclosporin, may allow for dose reductions of oral medication." @default.
- W62698972 created "2016-06-24" @default.
- W62698972 creator A5044488136 @default.
- W62698972 creator A5086116920 @default.
- W62698972 date "2005-05-14" @default.
- W62698972 modified "2023-09-23" @default.
- W62698972 title "[Topical immunomodulators, such as tacrolimus and pimecrolimus, in the treatment of atopic dermatitis]." @default.
- W62698972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15932135" @default.
- W62698972 hasPublicationYear "2005" @default.
- W62698972 type Work @default.
- W62698972 sameAs 62698972 @default.
- W62698972 citedByCount "1" @default.
- W62698972 crossrefType "journal-article" @default.
- W62698972 hasAuthorship W62698972A5044488136 @default.
- W62698972 hasAuthorship W62698972A5086116920 @default.
- W62698972 hasConcept C126322002 @default.
- W62698972 hasConcept C128057223 @default.
- W62698972 hasConcept C16005928 @default.
- W62698972 hasConcept C203014093 @default.
- W62698972 hasConcept C2776028589 @default.
- W62698972 hasConcept C2777063393 @default.
- W62698972 hasConcept C2778329239 @default.
- W62698972 hasConcept C2909675724 @default.
- W62698972 hasConcept C2911091166 @default.
- W62698972 hasConcept C71924100 @default.
- W62698972 hasConceptScore W62698972C126322002 @default.
- W62698972 hasConceptScore W62698972C128057223 @default.
- W62698972 hasConceptScore W62698972C16005928 @default.
- W62698972 hasConceptScore W62698972C203014093 @default.
- W62698972 hasConceptScore W62698972C2776028589 @default.
- W62698972 hasConceptScore W62698972C2777063393 @default.
- W62698972 hasConceptScore W62698972C2778329239 @default.
- W62698972 hasConceptScore W62698972C2909675724 @default.
- W62698972 hasConceptScore W62698972C2911091166 @default.
- W62698972 hasConceptScore W62698972C71924100 @default.
- W62698972 hasIssue "20" @default.
- W62698972 hasLocation W626989721 @default.
- W62698972 hasOpenAccess W62698972 @default.
- W62698972 hasPrimaryLocation W626989721 @default.
- W62698972 hasRelatedWork W1511797216 @default.
- W62698972 hasRelatedWork W1973386640 @default.
- W62698972 hasRelatedWork W2002068458 @default.
- W62698972 hasRelatedWork W2014666581 @default.
- W62698972 hasRelatedWork W2015770031 @default.
- W62698972 hasRelatedWork W2039185381 @default.
- W62698972 hasRelatedWork W2041471322 @default.
- W62698972 hasRelatedWork W2045844428 @default.
- W62698972 hasRelatedWork W2071715479 @default.
- W62698972 hasRelatedWork W2075878367 @default.
- W62698972 hasRelatedWork W2084224801 @default.
- W62698972 hasRelatedWork W2089887858 @default.
- W62698972 hasRelatedWork W2116671089 @default.
- W62698972 hasRelatedWork W2142684368 @default.
- W62698972 hasRelatedWork W2194797266 @default.
- W62698972 hasRelatedWork W2397769257 @default.
- W62698972 hasRelatedWork W2400784852 @default.
- W62698972 hasRelatedWork W2416963921 @default.
- W62698972 hasRelatedWork W2616348617 @default.
- W62698972 hasRelatedWork W2766730453 @default.
- W62698972 hasVolume "149" @default.
- W62698972 isParatext "false" @default.
- W62698972 isRetracted "false" @default.
- W62698972 magId "62698972" @default.
- W62698972 workType "article" @default.