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- W627196196 abstract "Elongated magnetic nanostructures, that is, magnetic nanowires, can be activated, controlled and manipulated remotely with the application of modest external magnetic fields. With their size and shape being experimentally set and controlled within a range of a few nm to several hundred nm, this puts them in a similar size category to biological entities (cells, bacteria, viruses, enzymes, genes or cell receptors) and therefore makes them very suitable for biomedical applications. In this chapter, the fundamentals of magnetic-nanowire magnetism are presented along with their synthesis methods, with a particular emphasis on electrodeposition. Multifunctional hybrid nanowires with dual magnetic and optical responses are further presented from the synthesis and application perspectives in sensing organic molecules. To perform as potential biomedical devices, for example, in bioseparations, the surface of the nanowires has to be first chemically and then biologically functionalized. The means of selective functionalization are presented in this chapter. To construct magnetic nanodevices, the functionalized nanowires are magnetically manipulated to specific points on microchips, where the responses with regard to sensing are measured. The same nanowires can be used for cell trapping, manipulation and separation. Based on the fact that they can be internalized within living cells, nanowires have been used to treat medical conditions such as cancer, either by exerting heat or mechanical forces on the targeted malignant cells. Even though nanowires were proven to be very versatile, not a lot of work has been dedicated to their cytotoxicity, with the latest findings gathered in this chapter. Fe-based nanowires were proven to be the least toxic and therefore acceptable in future nano/micromotor devices, which are looked at briefly at the end of the chapter." @default.
- W627196196 created "2016-06-24" @default.
- W627196196 creator A5018350496 @default.
- W627196196 date "2015-01-01" @default.
- W627196196 modified "2023-10-16" @default.
- W627196196 title "Functionalization of magnetic nanowires for biomedical applications" @default.
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