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• W629148114 abstract "To assess the effect of the Medtronic paclitaxel drug-eluting balloon (DEB) on re-intervention to in-stent stenoses in autogenous dialysis arteriovenous fistulas (AVFs).AVF is the optimum haemodialysis access. The commonest problem is stenosis, preventing maturation, causing inadequate dialysis or precipitating occlusion. Conventional angioplasty has a high recurrence rate. Successful drug elution in the coronary circulation led us to use DEBs in recurrent AVF stenoses since 2010.This is a retrospective study, based on prospective audit data, using DEBs on recurrent in-stent stenotic lesions in the AVF circuit of our haemodialysis population. To analyse the effect of DEBs on re-intervention, we created two Kaplan-Meier curves. The first curve compares the last disease-free-interval pre-DEB intervention to the first disease-free interval post-DEB, giving us re-intervention-free percentage at 12 months pre- and post-DEB. The second curve takes into account the multiple pre- and post-DEB interventions to the index lesion, and uses a marginal proportional hazards model to estimate the hazard ratio for DEBpresent vs. DEBabsent.From 1 September 2010 to 1 December 2013, we treated 625 AVF stenoses with endovascular techniques. In 86 of these stenoses, DEBs were used. Of the 86 DEB interventions, 37 were included for this study, 49 were excluded. In the study group, there was a significant difference in re-intervention-free percentage at 12 months before and after DEB: 19% vs. 69%. The hazard ratio for DEBpresent vs. DEBabsent was 0.23 (95% CI 0.14 to 0.36, p<0.001).This retrospective study suggests that DEBs significantly reduce re-intervention on recurrent in-stent AVF stenoses." @default.
• W629148114 created "2016-06-24" @default.
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• W629148114 date "2015-02-06" @default.
• W629148114 modified "2023-09-27" @default.
• W629148114 title "Paclitaxel Drug-eluting Balloons to Recurrent In-stent Stenoses in Autogenous Dialysis Fistulas: A Retrospective Study" @default.
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• W629148114 doi "https://doi.org/10.5301/jva.5000396" @default.
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