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• W63051451 abstract ". . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi CHAPTER 1. General introduction . . . . . . . . . . . . . . . . . . . . . . . . 1 1.1 Thesis organization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2 The immune response to intracellular pathogen . . . . . . . . . . . . . . . . . . 2 1.2.1 Innate immunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.2.2 Antigen processing and presentation . . . . . . . . . . . . . . . . . . . . 3 1.2.3 The adaptive immune response . . . . . . . . . . . . . . . . . . . . . . . 3 1.3 Leishmania infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3.1 Clinical diseases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 1.3.2 Transmission . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 1.3.3 Immunology of Leishmania major . . . . . . . . . . . . . . . . . . . . . 7 1.3.4 Treatment and vaccination . . . . . . . . . . . . . . . . . . . . . . . . . 8 1.4 Systems biology and computer modeling . . . . . . . . . . . . . . . . . . . . . . 9 1.4.1 The systems biology approach . . . . . . . . . . . . . . . . . . . . . . . . 9 1.4.2 Cellular automata and agent-based models . . . . . . . . . . . . . . . . 10" @default.
• W63051451 created "2016-06-24" @default.
• W63051451 creator A5011799414 @default.
• W63051451 date "2018-08-13" @default.
• W63051451 modified "2023-10-16" @default.
• W63051451 title "Exploring host-pathogen relationships through computer simulations of intracellular infection" @default.
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• W63051451 doi "https://doi.org/10.31274/rtd-180813-17036" @default.
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