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• W63176095 abstract "Chemokines are cytokines with chemotactic properties on inflammatory cells and other cell types. RANTES, MCP-1 and related molecules, constitute the C-C class of chemokine supergene family and a group of cytokines produced by hematopoietic cells, while IL-8 constitute the C-X-C class. The roles of most of these chemokines are not well known, although members of the chemokine family are inflammatory agents. The C-C chemokine plays a role in regulating Th-cell cytokine production and leukocyte trafficking. In this study we clearly show that RANTES and MCP-1 are mediators of acute inflammatory responses. Our report describes additional biological activities for RANTES, MCP-1, and IL-8, suggesting that these chemokines play a fundamental role in histamine and serotonin generation and cell function in mast cells." @default.
• W63176095 created "2016-06-24" @default.
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• W63176095 date "2010-04-14" @default.
• W63176095 modified "2023-10-16" @default.
• W63176095 title "Impact of RANTES, MCP-1 and IL-8 in mast cells." @default.
• W63176095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20385066" @default.
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