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- W632265947 abstract "A controlled clinical trial was undertaken to compare the efficacy of short course chemotherapygiven alone or combined with radical surgery in the treatment of spinal tuberculosis withoutparaplegia. Patients with active spinal tuberculosis involving the vertebral bodies and withoutparaplegia were randomly allocated to one of the following three regimens.(a) Rad 6 : Radical anterior resection with bone grafting plus six months of daily isoniazidand rifampicin.(b) Amb 6 : Ambulatory chemotherapy with six months of daily isoniazid and rifampicin, withoutsurgery.(c) Amb 9 : Same as (b) but the duration being nine months.The patients were intensively followed up for five years from the start. At five years, 98% of86 Amb 9, 91% of 82 Amb 6 and 88% of 82 Rad 6 patients had a favourable status. It is concludedthat ambulatory chemotherapy for 6 or 9 months is highly effective in the treatment of spinaltuberculosis. Radical surgery did not enhance the efficacy of the short course regimen." @default.
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- W632265947 date "1994-01-01" @default.
- W632265947 modified "2023-09-24" @default.
- W632265947 title "Five-year findings of a comparison of ambulatory short course chemotherapy with radical surgery plus chemotherapy for tuberculosis of the spine in Madras" @default.
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