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- W63262834 abstract "Apart from the thiol-specific/cholesterol-dependent cytolysin family of toxins (see Chapter 20) there are a number of other unrelated bacterial toxins that also have an affinity for plasma membrane cholesterol. Emphasis is given here on the Vibrio cholerae cytolysin (VCC) and the cytolysins from related Vibrio species. The inhibition of the cytolytic activity of these toxins by prior incubation with extracellular cholesterol or low density lipoprotein emerges as a unifying feature, as does plasma membrane cholesterol depletion. Incubation of VCC with cholesterol produces a heptameric oligomer, which is not equivalent to the pre-pore since it is unable to penetrate the plasma membrane. In structural terms, the precise sequence of VCC monomer binding to membrane, oligomer formation and pore insertion through the bilayer has yet to be fully defined. Several other bacterial toxins have a dependency for cholesterol, although the available data is limited in most cases." @default.
- W63262834 created "2016-06-24" @default.
- W63262834 creator A5022934794 @default.
- W63262834 creator A5042300878 @default.
- W63262834 date "2010-01-01" @default.
- W63262834 modified "2023-10-18" @default.
- W63262834 title "Cholesterol Specificity of Some Heptameric β-Barrel Pore-Forming Bacterial Toxins: Structural and Functional Aspects" @default.
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- W63262834 cites W1592344333 @default.
- W63262834 cites W1594502983 @default.
- W63262834 cites W1596462312 @default.
- W63262834 cites W1610696702 @default.
- W63262834 cites W1867057268 @default.
- W63262834 cites W1954988256 @default.
- W63262834 cites W1963304091 @default.
- W63262834 cites W1965851529 @default.
- W63262834 cites W1966833359 @default.
- W63262834 cites W1967230923 @default.
- W63262834 cites W1967289387 @default.
- W63262834 cites W1975661657 @default.
- W63262834 cites W1978503649 @default.
- W63262834 cites W1982836850 @default.
- W63262834 cites W1983928264 @default.
- W63262834 cites W1986503058 @default.
- W63262834 cites W1990173904 @default.
- W63262834 cites W1996852008 @default.
- W63262834 cites W1997219876 @default.
- W63262834 cites W1997769724 @default.
- W63262834 cites W2001009163 @default.
- W63262834 cites W2002320896 @default.
- W63262834 cites W2003459882 @default.
- W63262834 cites W2004466150 @default.
- W63262834 cites W200661156 @default.
- W63262834 cites W2012593448 @default.
- W63262834 cites W2015148410 @default.
- W63262834 cites W2016617866 @default.
- W63262834 cites W2017357789 @default.
- W63262834 cites W2018581315 @default.
- W63262834 cites W2021319373 @default.
- W63262834 cites W2021709633 @default.
- W63262834 cites W2023158247 @default.
- W63262834 cites W2025221802 @default.
- W63262834 cites W2025380988 @default.
- W63262834 cites W2027283953 @default.
- W63262834 cites W2034534720 @default.
- W63262834 cites W2041430507 @default.
- W63262834 cites W2043172280 @default.
- W63262834 cites W2047587272 @default.
- W63262834 cites W2049980665 @default.
- W63262834 cites W2051505438 @default.
- W63262834 cites W2054027422 @default.
- W63262834 cites W2056649293 @default.
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- W63262834 cites W2059734188 @default.
- W63262834 cites W2065010085 @default.
- W63262834 cites W2066878330 @default.
- W63262834 cites W2070553019 @default.
- W63262834 cites W2071194189 @default.
- W63262834 cites W2073038487 @default.
- W63262834 cites W2090327032 @default.
- W63262834 cites W2092255593 @default.
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- W63262834 doi "https://doi.org/10.1007/978-90-481-8622-8_21" @default.
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