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- W63303921 abstract "AbstractWith the tetracycline (Tc)-controlled gene expression system (Tet system), an experimental approach has been developed that permits alteration of individual gene activities in complex genetic systems in a truly conditional fashion, i.e., it is temporally defined, quantitative, and reversible. Monitoring the phenotypic changes that accompany such highly defined alterations has provided new insights into numerous biologic processes hereto not amenable to genetic dissection. The various versions of the Tet system (1–3) were successfully incorporated into a variety of model organisms such as Streptomyces cerevisiae, Dictyostelium, Drosophila, Arabidopsis, moss, mice, and rats (for review, see refs. 3–5).KeywordsMouse LineTranscription UnitBidirectional PromoterImmediate EarlyPosition Effect VariegationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W63303921 created "2016-06-24" @default.
- W63303921 creator A5011061047 @default.
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- W63303921 date "2003-11-15" @default.
- W63303921 modified "2023-09-22" @default.
- W63303921 title "Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression" @default.
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- W63303921 doi "https://doi.org/10.1385/1-59259-340-2:69" @default.
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