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- W63365034 abstract "为了在合成二乙三胺五乙酸-脱氧葡萄糖（DTPA-DG）基础上,制备^99Tc^m-DTPA-DG标记物,以SnCl2·2H2O为还原剂,还原^99Tc^mO4^-并与DTPA-DG形成^99Tc^m-DTPA-DG标记物.进行了DTPA-DG用量、SnCl2·2H2O用量、反应介质pH值、反应温度等对标记率的影响实验.结果表明,25 mg DTPA-DG,500 μg SnCl2·2H2O,pH=6,加入Na^99Tc^mO4淋洗液0.5～4 mL,在25℃以上放置30 min或沸水浴反应10 min时,用9 g/L NaCl和丙酮作展开剂纸层析法鉴定标记物,放射化学纯度＞99%.标记物在室温放置6 h,放射化学纯度仍达98.6%.^99Tc^m-DTPA-DG标记率高,标记物的体外稳定性好,操作简便,便于临床应用." @default.
- W63365034 created "2016-06-24" @default.
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- W63365034 date "2006-05-20" @default.
- W63365034 modified "2023-09-26" @default.
- W63365034 title "^99Tc^m-DTPA-DG标记物的制备" @default.
- W63365034 hasPublicationYear "2006" @default.
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