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- W633958194 abstract "目的探讨转化生长因子TGF—β1＋869T／C基因多态性与子痫前期的相关性。方法采用聚合酶链式反应一限制性片段长度多态性（Polymerase Chain Reaction with Restrition Fragment Length Polymo．phism，PCR—RFLP）技术检测156例子痫前期患者（子痫前期组）和252例正常妊娠健康孕妇（对照组）外周血的TGF-β1＋869T／C基因多态性，并对结果进行统计分析。结果TGF—β1基因＋869T／C位点存在CC、CT、TT三种基因型，子痫前期组CC基因型占33．33％，CT基因型占62．18％，TT基因型占4．49％；对照组CC基因型占13．10％，CT基因型占48．41％，TT基因型占38．49％。子痫前期组孕妇CC和CT基因型频率均明显高于对照组（P〈0．01，P〈0．01）；而TT基因型频率则明显低于对照组（P〈0．01）。子痫前期组＋869T／C位点C等位基因频率（64．42％）明显高于对照组（37．30％），T等位基因频率（35．58％）明显低于对照组（62．7％）。结论TGF—β1＋869T／C基因多态性与子痫前期显著相关。" @default.
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- W633958194 date "2014-01-01" @default.
- W633958194 modified "2023-09-24" @default.
- W633958194 title "转化生长因子TGF—β1＋869T／C基因多态性与子痫前期的相关性研究" @default.
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