FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W63503014> ?p ?o ?g. }

• W63503014 endingPage "466" @default.
• W63503014 startingPage "455" @default.
• W63503014 abstract "1. The work reported was designed to provide quantitative information about the capacity of the extrahepatic tissues of the rat to degrade injected VLD lipoproteins (very-low-density lipoproteins, d less than 1.006) to LD lipoproteins (low-density lipoproteins, d 1.006–1.063) and to study the fate of the different VLD-lipoprotein apoproteins during the degradative process. 2. Rat liver VLD lipoproteins, radioactively labelled in their protein moieties, were produced by the perfusion of the organ and were either injected into the circulation of the supradiaphragmatic rats or incubated in rat plasma at 37 degrees C. At a time (75 min) when approx. 90% of the triacylglycerol of the VLD lipoproteins had been hydrolysed the supradiaphragmatic rats were bled and VLD lipoproteins, LD lipoproteins and HD lipoproteins (high-density lipoproteins, d 1.063–1.21) were separated from their plasma and from the plasma incubated in vitro. The apoproteins of each of the lipoprotein classes were resolved by gel-filtration chromatography into three main fractions, designated peaks I, II and III. 3. Incubation of the liver VLD lipoproteins in plasma in vitro led to the transfer of about 30% of the total protein radioactivity to the HD lipoproteins. The transfer mainly involved the peak-II (arginine-rich and/or apo A-I) and peak-III (apo C) proteins. There was also a small transfer of radioactivity (about 5% of the total) to the LD lipoproteins. 4. Injection of the liver VLD lipoproteins into the circulation of the supradiaphragmatic rat resulted in the transfer of about 15% of the total VLD-lipoprotein radioactivity to the LD lipoproteins. The transfer involved mainly the peak-I (apo B) proteins and accounted for about 20% of the total apo B protein radioactivity of the injected VLD lipoproteins. When the endogenous plasma VLD lipoprotein was taken into account the transfer of apo B protein was about 35%. 5. The transfer of peak-II protein radioactivity from the VLD to the HD lipoproteins was greater in the plasma of the supradiaphragmatic rat than in the incubated plasma suggesting that there was a net transfer of peak-II apoproteins during the VLD lipoprotein degradation. The transfer of peak-III protein radioactivity was not greater in the plasma of the supradiaphragmatic rat, but there was a loss of this radioactivity from the circulation." @default.
• W63503014 created "2016-06-24" @default.
• W63503014 creator A5054168760 @default.
• W63503014 creator A5082918090 @default.
• W63503014 creator A5088450440 @default.
• W63503014 date "1979-02-15" @default.
• W63503014 modified "2023-10-16" @default.
• W63503014 title "The metabolic conversion of very-low-density lipoprotein into low-density lipoprotein by the extrahepatic tissues of the rat" @default.
• W63503014 cites W1040508368 @default.
• W63503014 cites W111700196 @default.
• W63503014 cites W144165635 @default.
• W63503014 cites W1484639187 @default.
• W63503014 cites W1498655121 @default.
• W63503014 cites W1499490708 @default.
• W63503014 cites W1504469181 @default.
• W63503014 cites W1511588285 @default.
• W63503014 cites W1512435793 @default.
• W63503014 cites W1564262981 @default.
• W63503014 cites W1571635754 @default.
• W63503014 cites W1775749144 @default.
• W63503014 cites W1849267736 @default.
• W63503014 cites W1946244962 @default.
• W63503014 cites W1963144433 @default.
• W63503014 cites W1988695592 @default.
• W63503014 cites W1990252630 @default.
• W63503014 cites W1994789322 @default.
• W63503014 cites W2008805998 @default.
• W63503014 cites W2008841515 @default.
• W63503014 cites W2011221882 @default.
• W63503014 cites W2013221314 @default.
• W63503014 cites W2015590956 @default.
• W63503014 cites W2019068323 @default.
• W63503014 cites W2022984783 @default.
• W63503014 cites W2024118357 @default.
• W63503014 cites W2030135168 @default.
• W63503014 cites W2037581676 @default.
• W63503014 cites W2041802340 @default.
• W63503014 cites W2044540043 @default.
• W63503014 cites W2045884514 @default.
• W63503014 cites W2049029276 @default.
• W63503014 cites W2059716866 @default.
• W63503014 cites W2060711109 @default.
• W63503014 cites W2070654483 @default.
• W63503014 cites W2075314216 @default.
• W63503014 cites W2087298783 @default.
• W63503014 cites W2088680838 @default.
• W63503014 cites W2113006405 @default.
• W63503014 cites W2116932350 @default.
• W63503014 cites W2117348699 @default.
• W63503014 cites W2135503869 @default.
• W63503014 cites W2184182369 @default.
• W63503014 cites W2405619387 @default.
• W63503014 cites W2413344286 @default.
• W63503014 cites W2422798502 @default.
• W63503014 cites W2474324535 @default.
• W63503014 doi "https://doi.org/10.1042/bj1780455" @default.
• W63503014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1186535" @default.
• W63503014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/220966" @default.
• W63503014 hasPublicationYear "1979" @default.
• W63503014 type Work @default.
• W63503014 sameAs 63503014 @default.
• W63503014 citedByCount "19" @default.
• W63503014 crossrefType "journal-article" @default.
• W63503014 hasAuthorship W63503014A5054168760 @default.
• W63503014 hasAuthorship W63503014A5082918090 @default.
• W63503014 hasAuthorship W63503014A5088450440 @default.
• W63503014 hasBestOaLocation W635030142 @default.
• W63503014 hasConcept C126322002 @default.
• W63503014 hasConcept C146957229 @default.
• W63503014 hasConcept C181199279 @default.
• W63503014 hasConcept C185592680 @default.
• W63503014 hasConcept C193363816 @default.
• W63503014 hasConcept C202751555 @default.
• W63503014 hasConcept C25642318 @default.
• W63503014 hasConcept C2778163477 @default.
• W63503014 hasConcept C2780072125 @default.
• W63503014 hasConcept C2993401043 @default.
• W63503014 hasConcept C43617362 @default.
• W63503014 hasConcept C45505151 @default.
• W63503014 hasConcept C55493867 @default.
• W63503014 hasConcept C71924100 @default.
• W63503014 hasConcept C8004288 @default.
• W63503014 hasConcept C8243546 @default.
• W63503014 hasConceptScore W63503014C126322002 @default.
• W63503014 hasConceptScore W63503014C146957229 @default.
• W63503014 hasConceptScore W63503014C181199279 @default.
• W63503014 hasConceptScore W63503014C185592680 @default.
• W63503014 hasConceptScore W63503014C193363816 @default.
• W63503014 hasConceptScore W63503014C202751555 @default.
• W63503014 hasConceptScore W63503014C25642318 @default.
• W63503014 hasConceptScore W63503014C2778163477 @default.
• W63503014 hasConceptScore W63503014C2780072125 @default.
• W63503014 hasConceptScore W63503014C2993401043 @default.
• W63503014 hasConceptScore W63503014C43617362 @default.
• W63503014 hasConceptScore W63503014C45505151 @default.
• W63503014 hasConceptScore W63503014C55493867 @default.
• W63503014 hasConceptScore W63503014C71924100 @default.
• W63503014 hasConceptScore W63503014C8004288 @default.

• next