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- W636006461 abstract "Objective To study the immunological activity of BCG-CpG-DNA. Methods Determine the immunological activity of BCG-CpG-DNA by lymphocyte proliferation test, T cell subgrouping, the production of cytokine and the effect on killing activity of NK cells. Results BCG-CpG-DNA promoted the proliferation of T and B lymphocytes in mice, activated macrophages to secrete IL-12, enhanced the ability of ConA in inducing IFN-γ, increased the contents of CD3(superscript +), CD4(superscript +) and CD8(superscript +) T cell subgroups in murine splenic cells and enhanced the killing activity of murine NK cells. All the results of test and control groups showed significant difference. Conclusion BCG-CpG-DNA activated antigen-presenting cells and showed good immunological activity." @default.
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- W636006461 date "2006-11-20" @default.
- W636006461 modified "2023-09-28" @default.
- W636006461 title "BCG-CpG-DNA免疫活性作用的初步研究" @default.
- W636006461 hasPublicationYear "2006" @default.
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