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- W63684443 abstract "AIM:To investigate the significance of the expression of Pglycoprotein and the relationship between its expression and the efficacy of chemotherapy in patients with gastric cancer. METHODS:P-glycoprotein was examined by immunohistochemical staining in 101 specimens of paraffin embedded gastric cancer tissues. RESULTS:The expression rates of P-glycoprotein in normal gastric mucosa, paracancerous tissues and gastric cancer tissues were 13 %, 22% and 43 %, respectively(P <0.05). The expression rates of P-glycoprotein in the highly and moderately differentiated tumors (58 % and 80 %, respectively) were significantly higher than those in the lowly and poorly differentiated tumors (36 % and 25 %, respectively) (P <0.01).The postoperative cumulative survival rate of the patients receiving chemotherapy was significantly higher than that of the patients without chemotherapy in Pglycoprotein-negative patients with gastric cancer (P <0.01)." @default.
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- W63684443 date "2003-01-01" @default.
- W63684443 modified "2023-10-18" @default.
- W63684443 title "Relationship between expression of P-glycoprotein and efficacy of chemotherapy in gastric cancer" @default.
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- W63684443 doi "https://doi.org/10.11569/wcjd.v11.i1.36" @default.
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